Influence of Ile655Val polymorphism on trastuzumab-induced cardiotoxicity in early-stage HER2 positive breast cancer

Influence of Ile655Val polymorphism on trastuzumab-induced cardiotoxicity in early-stage HER2 positive breast cancer

Abstract Trastuzumab has improved the prognosis of HER2 positive breast cancer, but cardiotoxicity remains a concern. We aimed to identify risk factors for trastuzumab-induced cardiotoxicity, with an emphasis on the HER2 Ile655Val single nucleotide polymorphism. This single-center case–control study...

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Autores principales: Ljubica Vazdar, Ivo Darko Gabrić, Ivan Kruljac, Hrvoje Pintarić, Robert Šeparović, Lora Stanka Kirigin Biloš, Mirjana Pavlović, Ana Tečić Vuger, Mario Štefanović
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b0792d63096946bf96cbd11450c1c581
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