Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis

Neutrophils play critical roles in the host response to bacteria, including the production neutrophil extracellular traps (NET). Here the authors show that NET formation in the context of pneumococcal meningitis impairs bacterial clearance and targeting NET formation in this context could be a poten...

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Autores principales:	Tirthankar Mohanty, Jane Fisher, Anahita Bakochi, Ariane Neumann, José Francisco Pereira Cardoso, Christofer A. Q. Karlsson, Chiara Pavan, Iben Lundgaard, Bo Nilson, Peter Reinstrup, Johan Bonnevier, David Cederberg, Johan Malmström, Peter Bentzer, Adam Linder
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b07c86bc32944286b1715bc59d4fafda
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spelling	oai:doaj.org-article:b07c86bc32944286b1715bc59d4fafda2021-12-02T17:32:10ZNeutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis10.1038/s41467-019-09040-02041-1723https://doaj.org/article/b07c86bc32944286b1715bc59d4fafda2019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09040-0https://doaj.org/toc/2041-1723Neutrophils play critical roles in the host response to bacteria, including the production neutrophil extracellular traps (NET). Here the authors show that NET formation in the context of pneumococcal meningitis impairs bacterial clearance and targeting NET formation in this context could be a potential therapeutic option.Tirthankar MohantyJane FisherAnahita BakochiAriane NeumannJosé Francisco Pereira CardosoChristofer A. Q. KarlssonChiara PavanIben LundgaardBo NilsonPeter ReinstrupJohan BonnevierDavid CederbergJohan MalmströmPeter BentzerAdam LinderNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tirthankar Mohanty Jane Fisher Anahita Bakochi Ariane Neumann José Francisco Pereira Cardoso Christofer A. Q. Karlsson Chiara Pavan Iben Lundgaard Bo Nilson Peter Reinstrup Johan Bonnevier David Cederberg Johan Malmström Peter Bentzer Adam Linder Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
description	Neutrophils play critical roles in the host response to bacteria, including the production neutrophil extracellular traps (NET). Here the authors show that NET formation in the context of pneumococcal meningitis impairs bacterial clearance and targeting NET formation in this context could be a potential therapeutic option.
format	article
author	Tirthankar Mohanty Jane Fisher Anahita Bakochi Ariane Neumann José Francisco Pereira Cardoso Christofer A. Q. Karlsson Chiara Pavan Iben Lundgaard Bo Nilson Peter Reinstrup Johan Bonnevier David Cederberg Johan Malmström Peter Bentzer Adam Linder
author_facet	Tirthankar Mohanty Jane Fisher Anahita Bakochi Ariane Neumann José Francisco Pereira Cardoso Christofer A. Q. Karlsson Chiara Pavan Iben Lundgaard Bo Nilson Peter Reinstrup Johan Bonnevier David Cederberg Johan Malmström Peter Bentzer Adam Linder
author_sort	Tirthankar Mohanty
title	Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
title_short	Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
title_full	Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
title_fullStr	Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
title_full_unstemmed	Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
title_sort	neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b07c86bc32944286b1715bc59d4fafda
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Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis

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