TMEM16F and dynamins control expansive plasma membrane reservoirs

Cells locally expand and retract their surface in response to environmental factors such as changes in membrane tension. Here the authors show the membrane adapter, dynamin2, locally constricts surface membrane to form an isolated but contiguous membrane reservoir that can open upon phospholipid scr...

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Autores principales: Christine Deisl, Donald W. Hilgemann, Ruhma Syeda, Michael Fine
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b08422acbb4f4d83b049757b6a3294e3
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spelling oai:doaj.org-article:b08422acbb4f4d83b049757b6a3294e32021-12-02T17:08:38ZTMEM16F and dynamins control expansive plasma membrane reservoirs10.1038/s41467-021-25286-z2041-1723https://doaj.org/article/b08422acbb4f4d83b049757b6a3294e32021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25286-zhttps://doaj.org/toc/2041-1723Cells locally expand and retract their surface in response to environmental factors such as changes in membrane tension. Here the authors show the membrane adapter, dynamin2, locally constricts surface membrane to form an isolated but contiguous membrane reservoir that can open upon phospholipid scrambling via TMEM16F.Christine DeislDonald W. HilgemannRuhma SyedaMichael FineNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Christine Deisl
Donald W. Hilgemann
Ruhma Syeda
Michael Fine
TMEM16F and dynamins control expansive plasma membrane reservoirs
description Cells locally expand and retract their surface in response to environmental factors such as changes in membrane tension. Here the authors show the membrane adapter, dynamin2, locally constricts surface membrane to form an isolated but contiguous membrane reservoir that can open upon phospholipid scrambling via TMEM16F.
format article
author Christine Deisl
Donald W. Hilgemann
Ruhma Syeda
Michael Fine
author_facet Christine Deisl
Donald W. Hilgemann
Ruhma Syeda
Michael Fine
author_sort Christine Deisl
title TMEM16F and dynamins control expansive plasma membrane reservoirs
title_short TMEM16F and dynamins control expansive plasma membrane reservoirs
title_full TMEM16F and dynamins control expansive plasma membrane reservoirs
title_fullStr TMEM16F and dynamins control expansive plasma membrane reservoirs
title_full_unstemmed TMEM16F and dynamins control expansive plasma membrane reservoirs
title_sort tmem16f and dynamins control expansive plasma membrane reservoirs
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/b08422acbb4f4d83b049757b6a3294e3
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