TMEM16F and dynamins control expansive plasma membrane reservoirs
Cells locally expand and retract their surface in response to environmental factors such as changes in membrane tension. Here the authors show the membrane adapter, dynamin2, locally constricts surface membrane to form an isolated but contiguous membrane reservoir that can open upon phospholipid scr...
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Nature Portfolio
2021
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oai:doaj.org-article:b08422acbb4f4d83b049757b6a3294e32021-12-02T17:08:38ZTMEM16F and dynamins control expansive plasma membrane reservoirs10.1038/s41467-021-25286-z2041-1723https://doaj.org/article/b08422acbb4f4d83b049757b6a3294e32021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25286-zhttps://doaj.org/toc/2041-1723Cells locally expand and retract their surface in response to environmental factors such as changes in membrane tension. Here the authors show the membrane adapter, dynamin2, locally constricts surface membrane to form an isolated but contiguous membrane reservoir that can open upon phospholipid scrambling via TMEM16F.Christine DeislDonald W. HilgemannRuhma SyedaMichael FineNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021) |
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Science Q Christine Deisl Donald W. Hilgemann Ruhma Syeda Michael Fine TMEM16F and dynamins control expansive plasma membrane reservoirs |
description |
Cells locally expand and retract their surface in response to environmental factors such as changes in membrane tension. Here the authors show the membrane adapter, dynamin2, locally constricts surface membrane to form an isolated but contiguous membrane reservoir that can open upon phospholipid scrambling via TMEM16F. |
format |
article |
author |
Christine Deisl Donald W. Hilgemann Ruhma Syeda Michael Fine |
author_facet |
Christine Deisl Donald W. Hilgemann Ruhma Syeda Michael Fine |
author_sort |
Christine Deisl |
title |
TMEM16F and dynamins control expansive plasma membrane reservoirs |
title_short |
TMEM16F and dynamins control expansive plasma membrane reservoirs |
title_full |
TMEM16F and dynamins control expansive plasma membrane reservoirs |
title_fullStr |
TMEM16F and dynamins control expansive plasma membrane reservoirs |
title_full_unstemmed |
TMEM16F and dynamins control expansive plasma membrane reservoirs |
title_sort |
tmem16f and dynamins control expansive plasma membrane reservoirs |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/b08422acbb4f4d83b049757b6a3294e3 |
work_keys_str_mv |
AT christinedeisl tmem16fanddynaminscontrolexpansiveplasmamembranereservoirs AT donaldwhilgemann tmem16fanddynaminscontrolexpansiveplasmamembranereservoirs AT ruhmasyeda tmem16fanddynaminscontrolexpansiveplasmamembranereservoirs AT michaelfine tmem16fanddynaminscontrolexpansiveplasmamembranereservoirs |
_version_ |
1718381517037633536 |