ERK5 Inhibition Induces Autophagy-Mediated Cancer Cell Death by Activating ER Stress
Autophagy is a highly conserved intracellular process that preserves cellular homeostasis by mediating the lysosomal degradation of virtually any component of the cytoplasm. Autophagy is a key instrument of cellular response to several stresses, including endoplasmic reticulum (ER) stress. Cancer ce...
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Auteurs principaux: | Andrés Gámez-García, Idoia Bolinaga-Ayala, Guillermo Yoldi, Sergio Espinosa-Gil, Nora Diéguez-Martínez, Elisabet Megías-Roda, Pau Muñoz-Guardiola, Jose M. Lizcano |
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Format: | article |
Langue: | EN |
Publié: |
Frontiers Media S.A.
2021
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Sujets: | |
Accès en ligne: | https://doaj.org/article/b087629e9a314cc7945f694a47bb7246 |
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