Epidemiology and Challenges of HBV/HIV Co-Infection Amongst HIV-Infected Patients in Endemic Areas: Review
Letebrhan Weldemhret Medical Microbiology, Tigray Health Research Institute, Mekelle, EthiopiaCorrespondence: Letebrhan Weldemhret Email Letinaweldemhret@gmail.comAbstract: With the introduction of highly active antiretroviral treatment, HIV-related morbidity and mortality have declined. But underly...
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| Format: | article |
| Language: | EN |
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Dove Medical Press
2021
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| Online Access: | https://doaj.org/article/b08f54d0d37b4829801294d03429d78d |
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| Summary: | Letebrhan Weldemhret Medical Microbiology, Tigray Health Research Institute, Mekelle, EthiopiaCorrespondence: Letebrhan Weldemhret Email Letinaweldemhret@gmail.comAbstract: With the introduction of highly active antiretroviral treatment, HIV-related morbidity and mortality have declined. But underlying hepatitis B virus infection remains the major cause of AIDS-defined illness and liver-related disease progression mainly in endemic settings. Moreover, HBV–HIV co-infection is the leading cause of cirrhosis, hepatocellular carcinoma, and liver-related death. This review paper emphasizes reviewing the burden and impact of HBV–HIV co-infection in liver-related disease progression, immune recovery, and therapeutic management of HIV-infected individuals on ART regimen.Keywords: epidemiology, HBV, HIV, HBV–HIV, co-infection, patient, endemic |
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