Does postoperative quantitative bone scintigraphy reflect outcomes following medial open-wedge high tibial osteotomy?

<h4>Purpose</h4>The present study evaluated changes in bone tracer uptake (BTU) after medial open-wedge high tibial osteotomy (MOWHTO) and determined whether postoperative BTU correlates with clinical symptoms, radiologic parameters, or cartilage regeneration following MOWHTO.<h4>M...

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Autores principales:	Jung-Kwon Bae, Kang-Il Kim, Jun-Ho Kim, Hyun-Gon Gwak, Chanwoo Kim
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b0958761c4f94074a3992fce44b208b2
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spelling	oai:doaj.org-article:b0958761c4f94074a3992fce44b208b22021-12-02T20:08:16ZDoes postoperative quantitative bone scintigraphy reflect outcomes following medial open-wedge high tibial osteotomy?1932-620310.1371/journal.pone.0257315https://doaj.org/article/b0958761c4f94074a3992fce44b208b22021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0257315https://doaj.org/toc/1932-6203<h4>Purpose</h4>The present study evaluated changes in bone tracer uptake (BTU) after medial open-wedge high tibial osteotomy (MOWHTO) and determined whether postoperative BTU correlates with clinical symptoms, radiologic parameters, or cartilage regeneration following MOWHTO.<h4>Methods</h4>A total of 210 knees underwent MOWHTO for medial compartmental osteoarthritis (OA) were enrolled in this study. Mean follow-up period was 42.7 months. We assessed BTU for the medial compartment of the knee before MOWHTO and at the time of plate removal. Radiologic parameters included Kellgren-Lawrence (K-L) grade and Hip-Knee-Ankle angle (HKAA). Clinical evaluation included American Knee Society (AKS) score and cartilage status was graded at the time of MOWHTO and second-look arthroscopy according to the International Cartilage Repair Society (ICRS) grading system and articular cartilage regeneration stage. Statistical analysis performed to assess the relationships among postoperative BTU of the medial compartment, radiologic parameters, arthroscopic changes and clinical outcomes.<h4>Results</h4>BTU of medial femoral condyle and tibial plateau were significantly decreased at 2 years after MOWHTO (p<0.001). AKS scores and arthroscopic cartilage status were also significantly improved following MOWHTO. BMI and postoperative HKAA showed significant correlations with postoperative changes of BTU in uni- and multi-variable analysis. Meanwhile, postoperative changes of BTU did not show significant correlation with clinical outcomes or cartilage regeneration following MOWHTO.<h4>Conclusion</h4>Lower BMI and postoperative valgus alignment were significant predictor for postoperative BTU decrease of the medial compartment following MOWHTO. However, postoperative changes of BTU did not reflect cartilage regeneration or clinical outcomes until the midterm follow-up.Jung-Kwon BaeKang-Il KimJun-Ho KimHyun-Gon GwakChanwoo KimPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 9, p e0257315 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jung-Kwon Bae Kang-Il Kim Jun-Ho Kim Hyun-Gon Gwak Chanwoo Kim Does postoperative quantitative bone scintigraphy reflect outcomes following medial open-wedge high tibial osteotomy?
description	<h4>Purpose</h4>The present study evaluated changes in bone tracer uptake (BTU) after medial open-wedge high tibial osteotomy (MOWHTO) and determined whether postoperative BTU correlates with clinical symptoms, radiologic parameters, or cartilage regeneration following MOWHTO.<h4>Methods</h4>A total of 210 knees underwent MOWHTO for medial compartmental osteoarthritis (OA) were enrolled in this study. Mean follow-up period was 42.7 months. We assessed BTU for the medial compartment of the knee before MOWHTO and at the time of plate removal. Radiologic parameters included Kellgren-Lawrence (K-L) grade and Hip-Knee-Ankle angle (HKAA). Clinical evaluation included American Knee Society (AKS) score and cartilage status was graded at the time of MOWHTO and second-look arthroscopy according to the International Cartilage Repair Society (ICRS) grading system and articular cartilage regeneration stage. Statistical analysis performed to assess the relationships among postoperative BTU of the medial compartment, radiologic parameters, arthroscopic changes and clinical outcomes.<h4>Results</h4>BTU of medial femoral condyle and tibial plateau were significantly decreased at 2 years after MOWHTO (p<0.001). AKS scores and arthroscopic cartilage status were also significantly improved following MOWHTO. BMI and postoperative HKAA showed significant correlations with postoperative changes of BTU in uni- and multi-variable analysis. Meanwhile, postoperative changes of BTU did not show significant correlation with clinical outcomes or cartilage regeneration following MOWHTO.<h4>Conclusion</h4>Lower BMI and postoperative valgus alignment were significant predictor for postoperative BTU decrease of the medial compartment following MOWHTO. However, postoperative changes of BTU did not reflect cartilage regeneration or clinical outcomes until the midterm follow-up.
format	article
author	Jung-Kwon Bae Kang-Il Kim Jun-Ho Kim Hyun-Gon Gwak Chanwoo Kim
author_facet	Jung-Kwon Bae Kang-Il Kim Jun-Ho Kim Hyun-Gon Gwak Chanwoo Kim
author_sort	Jung-Kwon Bae
title	Does postoperative quantitative bone scintigraphy reflect outcomes following medial open-wedge high tibial osteotomy?
title_short	Does postoperative quantitative bone scintigraphy reflect outcomes following medial open-wedge high tibial osteotomy?
title_full	Does postoperative quantitative bone scintigraphy reflect outcomes following medial open-wedge high tibial osteotomy?
title_fullStr	Does postoperative quantitative bone scintigraphy reflect outcomes following medial open-wedge high tibial osteotomy?
title_full_unstemmed	Does postoperative quantitative bone scintigraphy reflect outcomes following medial open-wedge high tibial osteotomy?
title_sort	does postoperative quantitative bone scintigraphy reflect outcomes following medial open-wedge high tibial osteotomy?
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/b0958761c4f94074a3992fce44b208b2
work_keys_str_mv	AT jungkwonbae doespostoperativequantitativebonescintigraphyreflectoutcomesfollowingmedialopenwedgehightibialosteotomy AT kangilkim doespostoperativequantitativebonescintigraphyreflectoutcomesfollowingmedialopenwedgehightibialosteotomy AT junhokim doespostoperativequantitativebonescintigraphyreflectoutcomesfollowingmedialopenwedgehightibialosteotomy AT hyungongwak doespostoperativequantitativebonescintigraphyreflectoutcomesfollowingmedialopenwedgehightibialosteotomy AT chanwookim doespostoperativequantitativebonescintigraphyreflectoutcomesfollowingmedialopenwedgehightibialosteotomy
_version_	1718375202262351872

Does postoperative quantitative bone scintigraphy reflect outcomes following medial open-wedge high tibial osteotomy?

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