Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw.
Inflammatory pain can be triggered by different stimuli, such as trauma, radiation, antigen and infection. In a model of inflammatory pain caused by infection, injection in the mice paw of lipopolysaccharide (LPS), a Toll-like receptor 4 (TLR4) agonist, produces mechanical hyperalgesia. We identify...
Guardado en:
Autores principales: | Igor L Calil, Ana C Zarpelon, Ana T G Guerrero, Jose C Alves-Filho, Sergio H Ferreira, Fernando Q Cunha, Thiago M Cunha, Waldiceu A Verri |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b09c2bc6c1ea48069bb39d41ac3d1b87 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
por: Jiro Sakai, et al.
Publicado: (2017) -
Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade.
por: Lindsay M Snyder, et al.
Publicado: (2021) -
Identification and function of myeloid differentiation factor 88 (MyD88) in Litopenaeus vannamei.
por: Shuang Zhang, et al.
Publicado: (2012) -
Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway
por: Chengcheng Li, et al.
Publicado: (2017) -
HPV-transformed cells exhibit altered HMGB1-TLR4/MyD88-SARM1 signaling axis
por: Mirian Galliote Morale, et al.
Publicado: (2018)