Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes

Genetic variation in natural populations could represent gene drive resistant alleles, preventing successful application for population management. Here the authors survey 1280 genomes from three mosquito species and concludes natural variation will not be detrimental to deploying gene drive technol...

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Autores principales:	Hanno Schmidt, Travis C. Collier, Mark J. Hanemaaijer, Parker D. Houston, Yoosook Lee, Gregory C. Lanzaro
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b0a39060fec94d51a16902c1f33c8a06
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spelling	oai:doaj.org-article:b0a39060fec94d51a16902c1f33c8a062021-12-02T16:56:31ZAbundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes10.1038/s41467-020-15204-02041-1723https://doaj.org/article/b0a39060fec94d51a16902c1f33c8a062020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15204-0https://doaj.org/toc/2041-1723Genetic variation in natural populations could represent gene drive resistant alleles, preventing successful application for population management. Here the authors survey 1280 genomes from three mosquito species and concludes natural variation will not be detrimental to deploying gene drive technology.Hanno SchmidtTravis C. CollierMark J. HanemaaijerParker D. HoustonYoosook LeeGregory C. LanzaroNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hanno Schmidt Travis C. Collier Mark J. Hanemaaijer Parker D. Houston Yoosook Lee Gregory C. Lanzaro Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes
description	Genetic variation in natural populations could represent gene drive resistant alleles, preventing successful application for population management. Here the authors survey 1280 genomes from three mosquito species and concludes natural variation will not be detrimental to deploying gene drive technology.
format	article
author	Hanno Schmidt Travis C. Collier Mark J. Hanemaaijer Parker D. Houston Yoosook Lee Gregory C. Lanzaro
author_facet	Hanno Schmidt Travis C. Collier Mark J. Hanemaaijer Parker D. Houston Yoosook Lee Gregory C. Lanzaro
author_sort	Hanno Schmidt
title	Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes
title_short	Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes
title_full	Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes
title_fullStr	Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes
title_full_unstemmed	Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes
title_sort	abundance of conserved crispr-cas9 target sites within the highly polymorphic genomes of anopheles and aedes mosquitoes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/b0a39060fec94d51a16902c1f33c8a06
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Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes

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