Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles

Circular dorsal ruffles (CDRs) are important for the vesicular uptake of extracellular matter, but the basis of their wave dynamics is not understood. Here, the authors propose and experimentally test a bistable reaction-diffusion system, which they show accounts for the typical CDR expansion and sh...

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Autores principales: Erik Bernitt, Hans-Günther Döbereiner, Nir S. Gov, Arik Yochelis
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/b0a7abdcb6774d989d06bfab761b2ebc
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spelling oai:doaj.org-article:b0a7abdcb6774d989d06bfab761b2ebc2021-12-02T14:41:18ZFronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles10.1038/ncomms158632041-1723https://doaj.org/article/b0a7abdcb6774d989d06bfab761b2ebc2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15863https://doaj.org/toc/2041-1723Circular dorsal ruffles (CDRs) are important for the vesicular uptake of extracellular matter, but the basis of their wave dynamics is not understood. Here, the authors propose and experimentally test a bistable reaction-diffusion system, which they show accounts for the typical CDR expansion and shrinkage and for aberrant formation of pinned waves and spirals.Erik BernittHans-Günther DöbereinerNir S. GovArik YochelisNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Erik Bernitt
Hans-Günther Döbereiner
Nir S. Gov
Arik Yochelis
Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
description Circular dorsal ruffles (CDRs) are important for the vesicular uptake of extracellular matter, but the basis of their wave dynamics is not understood. Here, the authors propose and experimentally test a bistable reaction-diffusion system, which they show accounts for the typical CDR expansion and shrinkage and for aberrant formation of pinned waves and spirals.
format article
author Erik Bernitt
Hans-Günther Döbereiner
Nir S. Gov
Arik Yochelis
author_facet Erik Bernitt
Hans-Günther Döbereiner
Nir S. Gov
Arik Yochelis
author_sort Erik Bernitt
title Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
title_short Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
title_full Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
title_fullStr Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
title_full_unstemmed Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
title_sort fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/b0a7abdcb6774d989d06bfab761b2ebc
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AT hansguntherdobereiner frontsandwavesofactinpolymerizationinabistabilitybasedmechanismofcirculardorsalruffles
AT nirsgov frontsandwavesofactinpolymerizationinabistabilitybasedmechanismofcirculardorsalruffles
AT arikyochelis frontsandwavesofactinpolymerizationinabistabilitybasedmechanismofcirculardorsalruffles
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