Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage

Qi et al. develop nucleus targeting graphene quantum dots (GQDs) by modifying amine-functionalised GQDs with nucleus targeting TAT peptides. The resulting functionalised GQDs exhibit good biocompatibility, nucleus uptake, and cancer cell targeting. They can suppress growth of cancer cells by selecti...

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Autores principales:	Lei Qi, Tonghe Pan, Liling Ou, Zhiqiang Ye, Chunlei Yu, Bijun Bao, Zixia Wu, Dayong Cao, Liming Dai
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/b0a7ad99f02648159a7db7a588304692
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spelling	oai:doaj.org-article:b0a7ad99f02648159a7db7a5883046922021-12-02T10:54:14ZBiocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage10.1038/s42003-021-01713-12399-3642https://doaj.org/article/b0a7ad99f02648159a7db7a5883046922021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01713-1https://doaj.org/toc/2399-3642Qi et al. develop nucleus targeting graphene quantum dots (GQDs) by modifying amine-functionalised GQDs with nucleus targeting TAT peptides. The resulting functionalised GQDs exhibit good biocompatibility, nucleus uptake, and cancer cell targeting. They can suppress growth of cancer cells by selectively inducing DNA damage.Lei QiTonghe PanLiling OuZhiqiang YeChunlei YuBijun BaoZixia WuDayong CaoLiming DaiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Lei Qi Tonghe Pan Liling Ou Zhiqiang Ye Chunlei Yu Bijun Bao Zixia Wu Dayong Cao Liming Dai Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage
description	Qi et al. develop nucleus targeting graphene quantum dots (GQDs) by modifying amine-functionalised GQDs with nucleus targeting TAT peptides. The resulting functionalised GQDs exhibit good biocompatibility, nucleus uptake, and cancer cell targeting. They can suppress growth of cancer cells by selectively inducing DNA damage.
format	article
author	Lei Qi Tonghe Pan Liling Ou Zhiqiang Ye Chunlei Yu Bijun Bao Zixia Wu Dayong Cao Liming Dai
author_facet	Lei Qi Tonghe Pan Liling Ou Zhiqiang Ye Chunlei Yu Bijun Bao Zixia Wu Dayong Cao Liming Dai
author_sort	Lei Qi
title	Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage
title_short	Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage
title_full	Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage
title_fullStr	Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage
title_full_unstemmed	Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage
title_sort	biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via dna damage
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b0a7ad99f02648159a7db7a588304692
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Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage

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