A simple two-state protein unfolds mechanically via multiple heterogeneous pathways at single-molecule resolution

Previous investigations have indicated that the model protein CspB folds in a simple two-state fashion. Here, the authors provide direct experimental evidence for that the energy landscape of two-state folding proteins is highly heterogeneous and that unfolding can occur via multiple pathways.

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Detalles Bibliográficos
Autores principales: Jörg Schönfelder, Raul Perez-Jimenez, Victor Muñoz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/b0aaa035d8944396b1adbf1983ac4d33
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