Normal Skin Cells Increase Aggressiveness of Cutaneous Melanoma by Promoting Epithelial-to-Mesenchymal Transition via Nodal and Wnt Activity

Melanoma is a lethal form of skin cancer triggered by genetic and environmental factors. Excision of early-stage, poorly aggressive melanoma often leads to a successful outcome; however, left undiagnosed these lesions can progress to metastatic disease. This research investigates whether the exposur...

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Bibliographic Details
Main Authors: Gustavo Untiveros, Lindsay Dezi, Megan Gillette, Julia Sidor, Luigi Strizzi
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
Wnt
Online Access:https://doaj.org/article/b0acb0ba4be743c2a2d75334b9b26946
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