A paradigm shift for the prevention and treatment of individual and global obesity

Arnold H Slyper Clalit Health Organization, Jerusalem 9514622, Israel Abstract: The prevalence of obesity and overweight has plateaued in developed countries, although at high levels, but in most parts of the world, it continues to increase. Current recommendations for preventing and treating obesit...

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Autor principal:	Slyper AH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Obesity appetite satiety nutrition Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/b0ae38b1fe4f477296e2409091d2b426
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spelling	oai:doaj.org-article:b0ae38b1fe4f477296e2409091d2b4262021-12-02T02:19:05ZA paradigm shift for the prevention and treatment of individual and global obesity1178-7007https://doaj.org/article/b0ae38b1fe4f477296e2409091d2b4262018-11-01T00:00:00Zhttps://www.dovepress.com/a-paradigm-shift-for-the-prevention-and-treatment-of-individual-and-gl-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Arnold H Slyper Clalit Health Organization, Jerusalem 9514622, Israel Abstract: The prevalence of obesity and overweight has plateaued in developed countries, although at high levels, but in most parts of the world, it continues to increase. Current recommendations for preventing and treating obesity are based mainly on the notion that overeating results from hedonic eating as a result of unlimited access to palatable foods, particularly those high in sugar and fat, and that hedonic centers are able to “override” the body’s homeostatic mechanisms. This article proposes that the homeostatic mechanisms affecting appetite and satiety are more important in chronic overeating, and that sufficient evidence exists for adopting a new paradigm for controlling individual and global obesity based on controlling energy homeostasis via the enteroendocrine and gut microbiota systems. Many obese children and adolescents have chronic hunger, supporting the notion that they have a homeostatic rather than hedonic abnormality. The effectiveness of weight loss drugs and bariatric surgery suggests that the brain centers controlling energy homeostasis are able to override centers controlling hedonic drives. Energy homeostasis can also be influenced by nutrition, in particular, by avoiding sweetened drinks and consuming whole grains, vegetables, fruits and other foods that are high in dietary fiber, and thereby influence appetite and satiety. New recommendations are outlined for preventing and treating individual and global obesity based on a paradigm that targets appetite and satiety. Keywords: obesity, appetite, satiety, nutritionSlyper AHDove Medical PressarticleObesityappetitesatietynutritionSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 11, Pp 855-861 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Obesity appetite satiety nutrition Specialties of internal medicine RC581-951
spellingShingle	Obesity appetite satiety nutrition Specialties of internal medicine RC581-951 Slyper AH A paradigm shift for the prevention and treatment of individual and global obesity
description	Arnold H Slyper Clalit Health Organization, Jerusalem 9514622, Israel Abstract: The prevalence of obesity and overweight has plateaued in developed countries, although at high levels, but in most parts of the world, it continues to increase. Current recommendations for preventing and treating obesity are based mainly on the notion that overeating results from hedonic eating as a result of unlimited access to palatable foods, particularly those high in sugar and fat, and that hedonic centers are able to “override” the body’s homeostatic mechanisms. This article proposes that the homeostatic mechanisms affecting appetite and satiety are more important in chronic overeating, and that sufficient evidence exists for adopting a new paradigm for controlling individual and global obesity based on controlling energy homeostasis via the enteroendocrine and gut microbiota systems. Many obese children and adolescents have chronic hunger, supporting the notion that they have a homeostatic rather than hedonic abnormality. The effectiveness of weight loss drugs and bariatric surgery suggests that the brain centers controlling energy homeostasis are able to override centers controlling hedonic drives. Energy homeostasis can also be influenced by nutrition, in particular, by avoiding sweetened drinks and consuming whole grains, vegetables, fruits and other foods that are high in dietary fiber, and thereby influence appetite and satiety. New recommendations are outlined for preventing and treating individual and global obesity based on a paradigm that targets appetite and satiety. Keywords: obesity, appetite, satiety, nutrition
format	article
author	Slyper AH
author_facet	Slyper AH
author_sort	Slyper AH
title	A paradigm shift for the prevention and treatment of individual and global obesity
title_short	A paradigm shift for the prevention and treatment of individual and global obesity
title_full	A paradigm shift for the prevention and treatment of individual and global obesity
title_fullStr	A paradigm shift for the prevention and treatment of individual and global obesity
title_full_unstemmed	A paradigm shift for the prevention and treatment of individual and global obesity
title_sort	paradigm shift for the prevention and treatment of individual and global obesity
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/b0ae38b1fe4f477296e2409091d2b426
work_keys_str_mv	AT slyperah aparadigmshiftforthepreventionandtreatmentofindividualandglobalobesity AT slyperah paradigmshiftforthepreventionandtreatmentofindividualandglobalobesity
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A paradigm shift for the prevention and treatment of individual and global obesity

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