Patent Foramen Ovale Closure: State of the Art

Patent foramen ovale (PFO) is a common abnormality affecting between 20% and 34% of the adult population. For most people, it is a benign finding; however, in some people, the PFO can open widely to enable paradoxical embolus to transit from the venous to arterial circulation, which is associated wi...

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Autores principales:	Joel P Giblett, Lynne K Williams, Stephen Kyranis, Leonard M Shapiro, Patrick A Calvert
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2020
Materias:	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/b0b35eff481a4b758dc4333903a978e9
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spelling	oai:doaj.org-article:b0b35eff481a4b758dc4333903a978e92021-12-04T16:03:46ZPatent Foramen Ovale Closure: State of the Art10.15420/icr.2019.271756-14851756-1477https://doaj.org/article/b0b35eff481a4b758dc4333903a978e92020-11-01T00:00:00Zhttps://www.icrjournal.com/articles/patent-foramen-ovale-closurehttps://doaj.org/toc/1756-1477https://doaj.org/toc/1756-1485Patent foramen ovale (PFO) is a common abnormality affecting between 20% and 34% of the adult population. For most people, it is a benign finding; however, in some people, the PFO can open widely to enable paradoxical embolus to transit from the venous to arterial circulation, which is associated with stroke and systemic embolisation. Percutaneous closure of the PFO in patients with cryptogenic stroke has been undertaken for a number of years, and a number of purpose-specific septal occluders have been marketed. Recent randomised control trials have demonstrated that closure of PFO in patients with cryptogenic stroke is associated with reduced rates of recurrent stroke. After a brief overview of the anatomy of a PFO, this article considers the evidence for PFO closure in cryptogenic stroke. The article also addresses other potential indications for closure, including systemic arterial embolisation, decompression sickness, platypnoea–orthodeoxia syndrome and migraine with aura. The article lays out the pre-procedural investigations and preparation for the procedure. Finally, the article gives an overview of the procedure itself, including discussion of closure devices.Joel P GiblettLynne K WilliamsStephen KyranisLeonard M ShapiroPatrick A CalvertRadcliffe Medical MediaarticleSurgeryRD1-811Diseases of the circulatory (Cardiovascular) systemRC666-701ENInterventional Cardiology: Reviews, Research, Resources, Vol 15, Iss , Pp - (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701 Joel P Giblett Lynne K Williams Stephen Kyranis Leonard M Shapiro Patrick A Calvert Patent Foramen Ovale Closure: State of the Art
description	Patent foramen ovale (PFO) is a common abnormality affecting between 20% and 34% of the adult population. For most people, it is a benign finding; however, in some people, the PFO can open widely to enable paradoxical embolus to transit from the venous to arterial circulation, which is associated with stroke and systemic embolisation. Percutaneous closure of the PFO in patients with cryptogenic stroke has been undertaken for a number of years, and a number of purpose-specific septal occluders have been marketed. Recent randomised control trials have demonstrated that closure of PFO in patients with cryptogenic stroke is associated with reduced rates of recurrent stroke. After a brief overview of the anatomy of a PFO, this article considers the evidence for PFO closure in cryptogenic stroke. The article also addresses other potential indications for closure, including systemic arterial embolisation, decompression sickness, platypnoea–orthodeoxia syndrome and migraine with aura. The article lays out the pre-procedural investigations and preparation for the procedure. Finally, the article gives an overview of the procedure itself, including discussion of closure devices.
format	article
author	Joel P Giblett Lynne K Williams Stephen Kyranis Leonard M Shapiro Patrick A Calvert
author_facet	Joel P Giblett Lynne K Williams Stephen Kyranis Leonard M Shapiro Patrick A Calvert
author_sort	Joel P Giblett
title	Patent Foramen Ovale Closure: State of the Art
title_short	Patent Foramen Ovale Closure: State of the Art
title_full	Patent Foramen Ovale Closure: State of the Art
title_fullStr	Patent Foramen Ovale Closure: State of the Art
title_full_unstemmed	Patent Foramen Ovale Closure: State of the Art
title_sort	patent foramen ovale closure: state of the art
publisher	Radcliffe Medical Media
publishDate	2020
url	https://doaj.org/article/b0b35eff481a4b758dc4333903a978e9
work_keys_str_mv	AT joelpgiblett patentforamenovaleclosurestateoftheart AT lynnekwilliams patentforamenovaleclosurestateoftheart AT stephenkyranis patentforamenovaleclosurestateoftheart AT leonardmshapiro patentforamenovaleclosurestateoftheart AT patrickacalvert patentforamenovaleclosurestateoftheart
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Patent Foramen Ovale Closure: State of the Art

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