Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008.

<h4>Background</h4>Prescribing of antibiotics for upper respiratory tract infections (URTI) varies substantially in primary care.<h4>Objectives</h4>To describe and compare antibiotic and antipyretic/anti-inflammatory drugs use, URTI symptoms' resolution and occurrence of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lamiae Grimaldi-Bensouda, Bernard Bégaud, Michel Rossignol, Bernard Avouac, France Lert, Frederic Rouillon, Jacques Bénichou, Jacques Massol, Gerard Duru, Anne-Marie Magnier, Lucien Abenhaim, Didier Guillemot
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b0ba0d5eb03e4d9d9536f802dc866459
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b0ba0d5eb03e4d9d9536f802dc866459
record_format	dspace
spelling	oai:doaj.org-article:b0ba0d5eb03e4d9d9536f802dc8664592021-11-18T08:27:26ZManagement of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008.1932-620310.1371/journal.pone.0089990https://doaj.org/article/b0ba0d5eb03e4d9d9536f802dc8664592014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24646513/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Prescribing of antibiotics for upper respiratory tract infections (URTI) varies substantially in primary care.<h4>Objectives</h4>To describe and compare antibiotic and antipyretic/anti-inflammatory drugs use, URTI symptoms' resolution and occurrence of potentially-associated infections in patients seeking care from general practitioners (GPs) who exclusively prescribe conventional medications (GP-CM), regularly prescribe homeopathy within a mixed practice (GP-Mx), or are certified homeopathic GPs (GP-Ho).<h4>Method</h4>The EPI3 survey was a nationwide population-based study of a representative sample of 825 GPs and their patients in France (2007-2008). GP recruitment was stratified by self-declared homeopathic prescribing preferences. Adults and children with confirmed URTI were asked to participate in a standardized telephone interview at inclusion, one-, three- and twelve-month follow up. Study outcomes included medication consumption, URTI symptoms' resolution and potentially-associated infections (sinusitis or otitis media/externa) as reported by patients. Analyses included calibration to account for non-respondents and groups were compared using multivate analyses adjusting for baseline differences with a propensity score.<h4>Results</h4>518 adults and children with URTI (79.3% rhinopharyngitis) were included (36.9% response rate comparable between groups). As opposed to GP-CM patients, patients in the GP-Ho group showed significantly lower consumption of antibiotics (Odds ratio (OR) = 0.43, 95% confidence interval (CI): 0.27-0.68) and antipyretic/anti-inflammatory drugs (OR = 0.54, 95% CI: 0.38-0.76) with similar evolution in related symptoms (OR = 1.16, 95% CI: 0.64-2.10). An excess of potentially-associated infections (OR = 1.70, 95% CI: 0.90-3.20) was observed in the GP-Ho group (not statistically significant). No difference was found between GP-CM and GP-Mx patients.<h4>Conclusion</h4>Patients who chose to consult GPs certified in homeopathy used less antibiotics and antipyretic/anti-inflammatory drugs for URTI than those seen by GPs prescribing conventional medications. No difference was observed in patients consulting GPs within mixed-practice. A non-statistically significant excess was estimated through modelling for associated infections in the GP-Ho group and needs to be further studied.Lamiae Grimaldi-BensoudaBernard BégaudMichel RossignolBernard AvouacFrance LertFrederic RouillonJacques BénichouJacques MassolGerard DuruAnne-Marie MagnierLucien AbenhaimDidier GuillemotPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 3, p e89990 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lamiae Grimaldi-Bensouda Bernard Bégaud Michel Rossignol Bernard Avouac France Lert Frederic Rouillon Jacques Bénichou Jacques Massol Gerard Duru Anne-Marie Magnier Lucien Abenhaim Didier Guillemot Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008.
description	<h4>Background</h4>Prescribing of antibiotics for upper respiratory tract infections (URTI) varies substantially in primary care.<h4>Objectives</h4>To describe and compare antibiotic and antipyretic/anti-inflammatory drugs use, URTI symptoms' resolution and occurrence of potentially-associated infections in patients seeking care from general practitioners (GPs) who exclusively prescribe conventional medications (GP-CM), regularly prescribe homeopathy within a mixed practice (GP-Mx), or are certified homeopathic GPs (GP-Ho).<h4>Method</h4>The EPI3 survey was a nationwide population-based study of a representative sample of 825 GPs and their patients in France (2007-2008). GP recruitment was stratified by self-declared homeopathic prescribing preferences. Adults and children with confirmed URTI were asked to participate in a standardized telephone interview at inclusion, one-, three- and twelve-month follow up. Study outcomes included medication consumption, URTI symptoms' resolution and potentially-associated infections (sinusitis or otitis media/externa) as reported by patients. Analyses included calibration to account for non-respondents and groups were compared using multivate analyses adjusting for baseline differences with a propensity score.<h4>Results</h4>518 adults and children with URTI (79.3% rhinopharyngitis) were included (36.9% response rate comparable between groups). As opposed to GP-CM patients, patients in the GP-Ho group showed significantly lower consumption of antibiotics (Odds ratio (OR) = 0.43, 95% confidence interval (CI): 0.27-0.68) and antipyretic/anti-inflammatory drugs (OR = 0.54, 95% CI: 0.38-0.76) with similar evolution in related symptoms (OR = 1.16, 95% CI: 0.64-2.10). An excess of potentially-associated infections (OR = 1.70, 95% CI: 0.90-3.20) was observed in the GP-Ho group (not statistically significant). No difference was found between GP-CM and GP-Mx patients.<h4>Conclusion</h4>Patients who chose to consult GPs certified in homeopathy used less antibiotics and antipyretic/anti-inflammatory drugs for URTI than those seen by GPs prescribing conventional medications. No difference was observed in patients consulting GPs within mixed-practice. A non-statistically significant excess was estimated through modelling for associated infections in the GP-Ho group and needs to be further studied.
format	article
author	Lamiae Grimaldi-Bensouda Bernard Bégaud Michel Rossignol Bernard Avouac France Lert Frederic Rouillon Jacques Bénichou Jacques Massol Gerard Duru Anne-Marie Magnier Lucien Abenhaim Didier Guillemot
author_facet	Lamiae Grimaldi-Bensouda Bernard Bégaud Michel Rossignol Bernard Avouac France Lert Frederic Rouillon Jacques Bénichou Jacques Massol Gerard Duru Anne-Marie Magnier Lucien Abenhaim Didier Guillemot
author_sort	Lamiae Grimaldi-Bensouda
title	Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008.
title_short	Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008.
title_full	Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008.
title_fullStr	Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008.
title_full_unstemmed	Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008.
title_sort	management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the epi3 cohort study in france 2007-2008.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/b0ba0d5eb03e4d9d9536f802dc866459
work_keys_str_mv	AT lamiaegrimaldibensouda managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT bernardbegaud managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT michelrossignol managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT bernardavouac managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT francelert managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT fredericrouillon managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT jacquesbenichou managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT jacquesmassol managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT gerardduru managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT annemariemagnier managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT lucienabenhaim managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008 AT didierguillemot managementofupperrespiratorytractinfectionsbydifferentmedicalpracticesincludinghomeopathyandconsumptionofantibioticsinprimarycaretheepi3cohortstudyinfrance20072008
_version_	1718421763070623744

Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008.

Ejemplares similares