The high methylation level of a novel 151-bp CpG island in the ESR1 gene promoter is associated with a poor breast cancer prognosis

The high methylation level of a novel 151-bp CpG island in the ESR1 gene promoter is associated with a poor breast cancer prognosis

Abstract Background The ESR1 gene suffers methylation changes in many types of cancers, including breast cancer (BC), the most frequently diagnosed cancer in women that is also present in men. Methylation at promoter A of ESR1 is the worse prognosis in terms of overall survival; thus, the early dete...

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Main Authors: Laura Itzel Quintas-Granados, Hernán Cortés, Manuel González-Del Carmen, Gerardo Leyva-Gómez, Lilia Patricia Bustamante-Montes, Miguel Rodríguez-Morales, Edgar Yebran Villegas-Vazquez, Israel López-Reyes, Sofía Lizeth Alcaraz-Estrada, Jorge Sandoval-Basilio, Ernesto Soto-Reyes, Javad Sharifi-Rad, Gabriela Figueroa-González, Octavio Daniel Reyes-Hernández
Format: article
Language:EN
Published: BMC 2021
Subjects:
Breast cancer
ESR1 methylation
Mexican women
Menopausal stage
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Cytology
QH573-671
Online Access:https://doaj.org/article/b0c28489a619489d88c83795437c70bd
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https://doaj.org/article/b0c28489a619489d88c83795437c70bd

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