Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation.
Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication, pathogenesis, drug, vaccine and gene-vector delivery, and as possible reservoirs of biomarkers. These findi...
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Public Library of Science (PLoS)
2012
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oai:doaj.org-article:b0c2f7b05ccd44f1b43fc0989fed5ece2021-11-18T05:37:19ZVesiclepedia: a compendium for extracellular vesicles with continuous community annotation.1544-91731545-788510.1371/journal.pbio.1001450https://doaj.org/article/b0c2f7b05ccd44f1b43fc0989fed5ece2012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23271954/pdf/?tool=EBIhttps://doaj.org/toc/1544-9173https://doaj.org/toc/1545-7885Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication, pathogenesis, drug, vaccine and gene-vector delivery, and as possible reservoirs of biomarkers. These findings have generated immense interest, along with an exponential increase in molecular data pertaining to EVs. Here, we describe Vesiclepedia, a manually curated compendium of molecular data (lipid, RNA, and protein) identified in different classes of EVs from more than 300 independent studies published over the past several years. Even though databases are indispensable resources for the scientific community, recent studies have shown that more than 50% of the databases are not regularly updated. In addition, more than 20% of the database links are inactive. To prevent such database and link decay, we have initiated a continuous community annotation project with the active involvement of EV researchers. The EV research community can set a gold standard in data sharing with Vesiclepedia, which could evolve as a primary resource for the field.Hina KalraRichard J SimpsonHong JiElena AikawaPeter AltevogtPhilip AskenaseVincent C BondFrancesc E BorràsXandra BreakefieldVivian BudnikEdit BuzasGiovanni CamussiAled ClaytonEmanuele CocucciJuan M Falcon-PerezSusanne GabrielssonYong Song GhoDwijendra GuptaH C HarshaAn HendrixAndrew F HillJameel M InalGuido JensterEva-Maria Krämer-AlbersSai Kiang LimAlicia LlorenteJan LötvallAntonio MarcillaLucia Mincheva-NilssonIrina NazarenkoRienk NieuwlandEsther N M Nolte-'t HoenAkhilesh PandeyTushar PatelMelissa G PiperStefano PluchinoT S Keshava PrasadLawrence RajendranGraca RaposoMichel RecordGavin E ReidFrancisco Sánchez-MadridRaymond M SchiffelersPia SiljanderAllan StensballeWillem StoorvogelDouglas TaylorClotilde TheryHadi ValadiBas W M van BalkomJesús VázquezMichel VidalMarca H M WaubenMaría Yáñez-MóMargot ZoellerSuresh MathivananPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Biology, Vol 10, Iss 12, p e1001450 (2012) |
| institution |
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| collection |
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| language |
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| topic |
Biology (General) QH301-705.5 |
| spellingShingle |
Biology (General) QH301-705.5 Hina Kalra Richard J Simpson Hong Ji Elena Aikawa Peter Altevogt Philip Askenase Vincent C Bond Francesc E Borràs Xandra Breakefield Vivian Budnik Edit Buzas Giovanni Camussi Aled Clayton Emanuele Cocucci Juan M Falcon-Perez Susanne Gabrielsson Yong Song Gho Dwijendra Gupta H C Harsha An Hendrix Andrew F Hill Jameel M Inal Guido Jenster Eva-Maria Krämer-Albers Sai Kiang Lim Alicia Llorente Jan Lötvall Antonio Marcilla Lucia Mincheva-Nilsson Irina Nazarenko Rienk Nieuwland Esther N M Nolte-'t Hoen Akhilesh Pandey Tushar Patel Melissa G Piper Stefano Pluchino T S Keshava Prasad Lawrence Rajendran Graca Raposo Michel Record Gavin E Reid Francisco Sánchez-Madrid Raymond M Schiffelers Pia Siljander Allan Stensballe Willem Stoorvogel Douglas Taylor Clotilde Thery Hadi Valadi Bas W M van Balkom Jesús Vázquez Michel Vidal Marca H M Wauben María Yáñez-Mó Margot Zoeller Suresh Mathivanan Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. |
| description |
Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication, pathogenesis, drug, vaccine and gene-vector delivery, and as possible reservoirs of biomarkers. These findings have generated immense interest, along with an exponential increase in molecular data pertaining to EVs. Here, we describe Vesiclepedia, a manually curated compendium of molecular data (lipid, RNA, and protein) identified in different classes of EVs from more than 300 independent studies published over the past several years. Even though databases are indispensable resources for the scientific community, recent studies have shown that more than 50% of the databases are not regularly updated. In addition, more than 20% of the database links are inactive. To prevent such database and link decay, we have initiated a continuous community annotation project with the active involvement of EV researchers. The EV research community can set a gold standard in data sharing with Vesiclepedia, which could evolve as a primary resource for the field. |
| format |
article |
| author |
Hina Kalra Richard J Simpson Hong Ji Elena Aikawa Peter Altevogt Philip Askenase Vincent C Bond Francesc E Borràs Xandra Breakefield Vivian Budnik Edit Buzas Giovanni Camussi Aled Clayton Emanuele Cocucci Juan M Falcon-Perez Susanne Gabrielsson Yong Song Gho Dwijendra Gupta H C Harsha An Hendrix Andrew F Hill Jameel M Inal Guido Jenster Eva-Maria Krämer-Albers Sai Kiang Lim Alicia Llorente Jan Lötvall Antonio Marcilla Lucia Mincheva-Nilsson Irina Nazarenko Rienk Nieuwland Esther N M Nolte-'t Hoen Akhilesh Pandey Tushar Patel Melissa G Piper Stefano Pluchino T S Keshava Prasad Lawrence Rajendran Graca Raposo Michel Record Gavin E Reid Francisco Sánchez-Madrid Raymond M Schiffelers Pia Siljander Allan Stensballe Willem Stoorvogel Douglas Taylor Clotilde Thery Hadi Valadi Bas W M van Balkom Jesús Vázquez Michel Vidal Marca H M Wauben María Yáñez-Mó Margot Zoeller Suresh Mathivanan |
| author_facet |
Hina Kalra Richard J Simpson Hong Ji Elena Aikawa Peter Altevogt Philip Askenase Vincent C Bond Francesc E Borràs Xandra Breakefield Vivian Budnik Edit Buzas Giovanni Camussi Aled Clayton Emanuele Cocucci Juan M Falcon-Perez Susanne Gabrielsson Yong Song Gho Dwijendra Gupta H C Harsha An Hendrix Andrew F Hill Jameel M Inal Guido Jenster Eva-Maria Krämer-Albers Sai Kiang Lim Alicia Llorente Jan Lötvall Antonio Marcilla Lucia Mincheva-Nilsson Irina Nazarenko Rienk Nieuwland Esther N M Nolte-'t Hoen Akhilesh Pandey Tushar Patel Melissa G Piper Stefano Pluchino T S Keshava Prasad Lawrence Rajendran Graca Raposo Michel Record Gavin E Reid Francisco Sánchez-Madrid Raymond M Schiffelers Pia Siljander Allan Stensballe Willem Stoorvogel Douglas Taylor Clotilde Thery Hadi Valadi Bas W M van Balkom Jesús Vázquez Michel Vidal Marca H M Wauben María Yáñez-Mó Margot Zoeller Suresh Mathivanan |
| author_sort |
Hina Kalra |
| title |
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. |
| title_short |
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. |
| title_full |
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. |
| title_fullStr |
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. |
| title_full_unstemmed |
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. |
| title_sort |
vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2012 |
| url |
https://doaj.org/article/b0c2f7b05ccd44f1b43fc0989fed5ece |
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