Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line

Pudewell et al. discuss and advance our understanding of accessory proteins, which are crucial for the RTK-RAS-MAPK signalling cascade. They consider the therapeutic potential of targeting such modulators as an alternative to targeting constituent components of the RTK-RAS-MAPK signalling cascade in...

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Auteurs principaux: Silke Pudewell, Christoph Wittich, Neda S. Kazemein Jasemi, Farhad Bazgir, Mohammad R. Ahmadian
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/b0d12c1b52df4beda6fee1cbf96887b8
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spelling oai:doaj.org-article:b0d12c1b52df4beda6fee1cbf96887b82021-12-02T17:34:48ZAccessory proteins of the RAS-MAPK pathway: moving from the side line to the front line10.1038/s42003-021-02149-32399-3642https://doaj.org/article/b0d12c1b52df4beda6fee1cbf96887b82021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02149-3https://doaj.org/toc/2399-3642Pudewell et al. discuss and advance our understanding of accessory proteins, which are crucial for the RTK-RAS-MAPK signalling cascade. They consider the therapeutic potential of targeting such modulators as an alternative to targeting constituent components of the RTK-RAS-MAPK signalling cascade in the treatment of diseases such as cancer.Silke PudewellChristoph WittichNeda S. Kazemein JasemiFarhad BazgirMohammad R. AhmadianNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Silke Pudewell
Christoph Wittich
Neda S. Kazemein Jasemi
Farhad Bazgir
Mohammad R. Ahmadian
Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line
description Pudewell et al. discuss and advance our understanding of accessory proteins, which are crucial for the RTK-RAS-MAPK signalling cascade. They consider the therapeutic potential of targeting such modulators as an alternative to targeting constituent components of the RTK-RAS-MAPK signalling cascade in the treatment of diseases such as cancer.
format article
author Silke Pudewell
Christoph Wittich
Neda S. Kazemein Jasemi
Farhad Bazgir
Mohammad R. Ahmadian
author_facet Silke Pudewell
Christoph Wittich
Neda S. Kazemein Jasemi
Farhad Bazgir
Mohammad R. Ahmadian
author_sort Silke Pudewell
title Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line
title_short Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line
title_full Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line
title_fullStr Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line
title_full_unstemmed Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line
title_sort accessory proteins of the ras-mapk pathway: moving from the side line to the front line
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/b0d12c1b52df4beda6fee1cbf96887b8
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AT farhadbazgir accessoryproteinsoftherasmapkpathwaymovingfromthesidelinetothefrontline
AT mohammadrahmadian accessoryproteinsoftherasmapkpathwaymovingfromthesidelinetothefrontline
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