Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase

Mevalonate diphosphate decarboxylase (MDD) is a key enzyme in the mevalonate pathway and catalyses the decarboxylation of mevalonate-5-diphosphate to isopentenyl diphosphate. Here, the authors provide insights into the conformational changes that occur during substrate binding of MDD and the subsequ...

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Bibliographic Details
Main Authors: Chun-Liang Chen, Lake N. Paul, James C. Mermoud, Calvin Nicklaus Steussy, Cynthia V. Stauffacher
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/b0d17fe2854d4bb9a893293053f08b6e
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