Lifespan and healthspan benefits of exogenous H2S in C. elegans are independent from effects downstream of eat-2 mutation

Abstract Caloric restriction (CR) is one of the most effective interventions to prolong lifespan and promote health. Recently, it has been suggested that hydrogen sulfide (H2S) may play a pivotal role in mediating some of these CR-associated benefits. While toxic at high concentrations, H2S at lower...

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Bibliographic Details
Main Authors: Li Theng Ng, Li Fang Ng, Richard Ming Yi Tang, Diogo Barardo, Barry Halliwell, Philip Keith Moore, Jan Gruber
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/b0d8bd33beb746bda80e4ac101a4e47c
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