Serum apolipoprotein A-I potentiates the therapeutic efficacy of lysocin E against Staphylococcus aureus
Lysocin E is a lipopeptide with antibiotic activity against methicillin-resistant Staphylococcus aureus. Here, the authors show that the antimicrobial activity of lysocin E is potentiated through interactions with host serum proteins (such as apolipoprotein A-I) and bacterial membrane components.
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Auteurs principaux: | Hiroshi Hamamoto, Suresh Panthee, Atmika Paudel, Kenichi Ishii, Jyunichiro Yasukawa, Jie Su, Atsushi Miyashita, Hiroaki Itoh, Kotaro Tokumoto, Masayuki Inoue, Kazuhisa Sekimizu |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Sujets: | |
Accès en ligne: | https://doaj.org/article/b0d96c9f5e974962964e3a02e7b2c23b |
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