Klebsiella pneumoniae necrotizing fasciitis of the leg in an elderly French woman

Marguerite Monié,1 Laurence Drieux,2–4 Bernadette Nzili,1 Michèle Dicko,5 Catherine Goursot,1 Sandrine Greffard,6 Dominique Decré,3,4,7 Anthony Mézière1 1Assistance Publique-Hôpitaux de Paris (AP-HP), GHU Pitié Sa...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Monié M, Drieux L, Nzili B, Dicko M, Goursot C, Greffard S, Decré D, Mézière A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Klebsiella pneumoniae - Necrotizing FasciitisE- Elderly Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/b0de28c85ebc4bc5b5c34ecadf3fdfe1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b0de28c85ebc4bc5b5c34ecadf3fdfe1
record_format	dspace
spelling	oai:doaj.org-article:b0de28c85ebc4bc5b5c34ecadf3fdfe12021-12-02T00:03:41ZKlebsiella pneumoniae necrotizing fasciitis of the leg in an elderly French woman1178-1998https://doaj.org/article/b0de28c85ebc4bc5b5c34ecadf3fdfe12014-07-01T00:00:00Zhttps://www.dovepress.com/klebsiella-pneumoniae-necrotizing-fasciitis-of-the-leg-in-an-elderly-f-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Marguerite Monié,1 Laurence Drieux,2–4 Bernadette Nzili,1 Michèle Dicko,5 Catherine Goursot,1 Sandrine Greffard,6 Dominique Decré,3,4,7 Anthony Mézière1 1Assistance Publique-Hôpitaux de Paris (AP-HP), GHU Pitié Salpêtrière-Charles Foix, site Charles Foix, Service de Soins de Suite et Réadaptation orthogériatrique et polyvalent, Fondation d’Heur et Chemin Delatour, Ivry s/Seine, 2Assistance Publique-Hôpitaux de Paris, Hôpital Charles-Foix, Bactériologie-Hygiène, Paris, 3Sorbonne Universités, UPMC Univ Paris 06, CR7, Centre d’Immunologie et des Maladies Infectieuses, CIMI, team E13 (Bacteriology), Paris, 4INSERM, U1135, Centre d’Immunologie et des Maladies Infectieuses, CIMI, team E13 (Bacteriology), Paris, 5AP-HP, GHU Henri Mondor, Département de Médecine Interne et Gériatrie, Créteil, 6AP-HP, GHU Pitié Salpêtrière-Charles Foix, site Pitié Salpêtrière, Service de Médecine Gériatrique, Paris, 7AP-HP, Hôpital Saint-Antoine, Bactériologie-Hygiène, Paris, France Abstract: Klebsiella pneumoniae necrotizing fasciitis is a rare infection in regions outside of Asia. Here, we present a case of necrotizing fasciitis of the leg caused by K. pneumoniae in a 92-year-old French woman hospitalized in a geriatric rehabilitation unit. The patient initially presented with dermohypodermitis of the leg that developed from a dirty wound following a fall. A few hours later, this painful injury extended to the entire lower limb, with purplish discoloration of the skin, bullae, and necrosis. Septic shock rapidly appeared and the patient died 9 hours after the onset of symptoms. The patient was Caucasian, with no history of travel to Asia or any underlying disease. Computed tomography revealed no infectious metastatic loci. Blood cultures showed growth of capsular serotype K2 K. pneumoniae strains with virulence factors RmpA, yersiniabactin and aerobactin. This rare and fatal case of necrotizing fasciitis caused by a virulent strain of K. pneumoniae occurred in a hospitalized elderly woman without risk factors. Clinicians and geriatricians in particular should be aware of this important albeit unusual differential diagnosis. Keywords: necrotizing fasciitis, Klebsiella pneumoniae, elderlyMonié MDrieux LNzili BDicko MGoursot CGreffard SDecré DMézière ADove Medical PressarticleKlebsiella pneumoniae - Necrotizing FasciitisE- ElderlyGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 1171-1174 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Klebsiella pneumoniae - Necrotizing FasciitisE- Elderly Geriatrics RC952-954.6
spellingShingle	Klebsiella pneumoniae - Necrotizing FasciitisE- Elderly Geriatrics RC952-954.6 Monié M Drieux L Nzili B Dicko M Goursot C Greffard S Decré D Mézière A Klebsiella pneumoniae necrotizing fasciitis of the leg in an elderly French woman
description	Marguerite Monié,1 Laurence Drieux,2–4 Bernadette Nzili,1 Michèle Dicko,5 Catherine Goursot,1 Sandrine Greffard,6 Dominique Decré,3,4,7 Anthony Mézière1 1Assistance Publique-Hôpitaux de Paris (AP-HP), GHU Pitié Salpêtrière-Charles Foix, site Charles Foix, Service de Soins de Suite et Réadaptation orthogériatrique et polyvalent, Fondation d’Heur et Chemin Delatour, Ivry s/Seine, 2Assistance Publique-Hôpitaux de Paris, Hôpital Charles-Foix, Bactériologie-Hygiène, Paris, 3Sorbonne Universités, UPMC Univ Paris 06, CR7, Centre d’Immunologie et des Maladies Infectieuses, CIMI, team E13 (Bacteriology), Paris, 4INSERM, U1135, Centre d’Immunologie et des Maladies Infectieuses, CIMI, team E13 (Bacteriology), Paris, 5AP-HP, GHU Henri Mondor, Département de Médecine Interne et Gériatrie, Créteil, 6AP-HP, GHU Pitié Salpêtrière-Charles Foix, site Pitié Salpêtrière, Service de Médecine Gériatrique, Paris, 7AP-HP, Hôpital Saint-Antoine, Bactériologie-Hygiène, Paris, France Abstract: Klebsiella pneumoniae necrotizing fasciitis is a rare infection in regions outside of Asia. Here, we present a case of necrotizing fasciitis of the leg caused by K. pneumoniae in a 92-year-old French woman hospitalized in a geriatric rehabilitation unit. The patient initially presented with dermohypodermitis of the leg that developed from a dirty wound following a fall. A few hours later, this painful injury extended to the entire lower limb, with purplish discoloration of the skin, bullae, and necrosis. Septic shock rapidly appeared and the patient died 9 hours after the onset of symptoms. The patient was Caucasian, with no history of travel to Asia or any underlying disease. Computed tomography revealed no infectious metastatic loci. Blood cultures showed growth of capsular serotype K2 K. pneumoniae strains with virulence factors RmpA, yersiniabactin and aerobactin. This rare and fatal case of necrotizing fasciitis caused by a virulent strain of K. pneumoniae occurred in a hospitalized elderly woman without risk factors. Clinicians and geriatricians in particular should be aware of this important albeit unusual differential diagnosis. Keywords: necrotizing fasciitis, Klebsiella pneumoniae, elderly
format	article
author	Monié M Drieux L Nzili B Dicko M Goursot C Greffard S Decré D Mézière A
author_facet	Monié M Drieux L Nzili B Dicko M Goursot C Greffard S Decré D Mézière A
author_sort	Monié M
title	Klebsiella pneumoniae necrotizing fasciitis of the leg in an elderly French woman
title_short	Klebsiella pneumoniae necrotizing fasciitis of the leg in an elderly French woman
title_full	Klebsiella pneumoniae necrotizing fasciitis of the leg in an elderly French woman
title_fullStr	Klebsiella pneumoniae necrotizing fasciitis of the leg in an elderly French woman
title_full_unstemmed	Klebsiella pneumoniae necrotizing fasciitis of the leg in an elderly French woman
title_sort	klebsiella pneumoniae necrotizing fasciitis of the leg in an elderly french woman
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/b0de28c85ebc4bc5b5c34ecadf3fdfe1
work_keys_str_mv	AT moniem klebsiellapneumoniaenecrotizingfasciitisoftheleginanelderlyfrenchwoman AT drieuxl klebsiellapneumoniaenecrotizingfasciitisoftheleginanelderlyfrenchwoman AT nzilib klebsiellapneumoniaenecrotizingfasciitisoftheleginanelderlyfrenchwoman AT dickom klebsiellapneumoniaenecrotizingfasciitisoftheleginanelderlyfrenchwoman AT goursotc klebsiellapneumoniaenecrotizingfasciitisoftheleginanelderlyfrenchwoman AT greffards klebsiellapneumoniaenecrotizingfasciitisoftheleginanelderlyfrenchwoman AT decred klebsiellapneumoniaenecrotizingfasciitisoftheleginanelderlyfrenchwoman AT mezierea klebsiellapneumoniaenecrotizingfasciitisoftheleginanelderlyfrenchwoman
_version_	1718403948421840896

Klebsiella pneumoniae necrotizing fasciitis of the leg in an elderly French woman

Ejemplares similares