Optimal management of breast cancer in the elderly patient: current perspectives

Olivia Le Saux,1 Bertrand Ripamonti,2 Amandine Bruyas,3,4 Olivier Bonin,4 Gilles Freyer,1,4 Marc Bonnefoy,4,5 Claire Falandry4,51Medical Oncology Unit, Lyon Sud University Hospital, Hospices Civils de Lyon, Pierre-Bénite, 2Gynaecology-Obstetrics Department, University Hospital, Saint-Etie...

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Autores principales:	Le Saux O, Ripamonti B, Bruyas A, Bonin O, Freyer G, Bonnefoy M, Falandry C
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	elderly geriatric assessment breast cancer surgery chemotherapy radiotherapy Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/b0e192e4da9e489694d548408dca8acb
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spelling	oai:doaj.org-article:b0e192e4da9e489694d548408dca8acb2021-12-02T01:37:53ZOptimal management of breast cancer in the elderly patient: current perspectives1178-1998https://doaj.org/article/b0e192e4da9e489694d548408dca8acb2015-01-01T00:00:00Zhttps://www.dovepress.com/optimal-management-of-breast-cancer-in-the-elderly-patient-current-per-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Olivia Le Saux,1 Bertrand Ripamonti,2 Amandine Bruyas,3,4 Olivier Bonin,4 Gilles Freyer,1,4 Marc Bonnefoy,4,5 Claire Falandry4,51Medical Oncology Unit, Lyon Sud University Hospital, Hospices Civils de Lyon, Pierre-Bénite, 2Gynaecology-Obstetrics Department, University Hospital, Saint-Etienne, 3Croix Rousse University Hospital, Hospices Civils de Lyon, Pierre-Bénite, 4Lyon University, Lyon, 5Geriatric Unit, Lyon Sud University Hospital, Hospices Civils de Lyon, Pierre-Bénite, FranceAbstract: Breast cancer (BC) is the most common female malignancy in the world and almost one third of cases occur after 70 years of age. Optimal management of BC in the elderly is a real challenge and requires a multidisciplinary approach, mainly because the elderly population is heterogeneous. In this review, we describe the various possibilities of treatment for localized or metastatic BC in an aging population. We provide an overview of the comprehensive geriatric assessment, surgery, radiotherapy, and adjuvant therapy for early localized BC and of chemotherapy and targeted therapies for metastatic BC. Finally, we attempt to put into perspective the necessary balance between the expected benefits and risks, especially in the adjuvant setting.Keywords: elderly, breast cancer, geriatric assessment, surgery, chemotherapy, radiotherapyLe Saux ORipamonti BBruyas ABonin OFreyer GBonnefoy MFalandry CDove Medical Pressarticleelderlygeriatric assessmentbreast cancersurgerychemotherapyradiotherapyGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 10, Pp 157-174 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	elderly geriatric assessment breast cancer surgery chemotherapy radiotherapy Geriatrics RC952-954.6
spellingShingle	elderly geriatric assessment breast cancer surgery chemotherapy radiotherapy Geriatrics RC952-954.6 Le Saux O Ripamonti B Bruyas A Bonin O Freyer G Bonnefoy M Falandry C Optimal management of breast cancer in the elderly patient: current perspectives
description	Olivia Le Saux,1 Bertrand Ripamonti,2 Amandine Bruyas,3,4 Olivier Bonin,4 Gilles Freyer,1,4 Marc Bonnefoy,4,5 Claire Falandry4,51Medical Oncology Unit, Lyon Sud University Hospital, Hospices Civils de Lyon, Pierre-Bénite, 2Gynaecology-Obstetrics Department, University Hospital, Saint-Etienne, 3Croix Rousse University Hospital, Hospices Civils de Lyon, Pierre-Bénite, 4Lyon University, Lyon, 5Geriatric Unit, Lyon Sud University Hospital, Hospices Civils de Lyon, Pierre-Bénite, FranceAbstract: Breast cancer (BC) is the most common female malignancy in the world and almost one third of cases occur after 70 years of age. Optimal management of BC in the elderly is a real challenge and requires a multidisciplinary approach, mainly because the elderly population is heterogeneous. In this review, we describe the various possibilities of treatment for localized or metastatic BC in an aging population. We provide an overview of the comprehensive geriatric assessment, surgery, radiotherapy, and adjuvant therapy for early localized BC and of chemotherapy and targeted therapies for metastatic BC. Finally, we attempt to put into perspective the necessary balance between the expected benefits and risks, especially in the adjuvant setting.Keywords: elderly, breast cancer, geriatric assessment, surgery, chemotherapy, radiotherapy
format	article
author	Le Saux O Ripamonti B Bruyas A Bonin O Freyer G Bonnefoy M Falandry C
author_facet	Le Saux O Ripamonti B Bruyas A Bonin O Freyer G Bonnefoy M Falandry C
author_sort	Le Saux O
title	Optimal management of breast cancer in the elderly patient: current perspectives
title_short	Optimal management of breast cancer in the elderly patient: current perspectives
title_full	Optimal management of breast cancer in the elderly patient: current perspectives
title_fullStr	Optimal management of breast cancer in the elderly patient: current perspectives
title_full_unstemmed	Optimal management of breast cancer in the elderly patient: current perspectives
title_sort	optimal management of breast cancer in the elderly patient: current perspectives
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/b0e192e4da9e489694d548408dca8acb
work_keys_str_mv	AT lesauxo optimalmanagementofbreastcancerintheelderlypatientcurrentperspectives AT ripamontib optimalmanagementofbreastcancerintheelderlypatientcurrentperspectives AT bruyasa optimalmanagementofbreastcancerintheelderlypatientcurrentperspectives AT bonino optimalmanagementofbreastcancerintheelderlypatientcurrentperspectives AT freyerg optimalmanagementofbreastcancerintheelderlypatientcurrentperspectives AT bonnefoym optimalmanagementofbreastcancerintheelderlypatientcurrentperspectives AT falandryc optimalmanagementofbreastcancerintheelderlypatientcurrentperspectives
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Optimal management of breast cancer in the elderly patient: current perspectives

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