Nanoparticles from Gantrez-based conjugates for the oral delivery of camptothecin

Camptothecin (CPT) exhibits a number of challenges for its oral administration, including a low aqueous solubility, a lactone ring susceptible to hydrolysis, and an affinity to the intestinal P-gp. The aim of this work was to evaluate nanoparticles from Gantrez-based conjugates as carriers for the o...

Full description

Saved in:
Bibliographic Details
Main Authors: Judit Huarte, Socorro Espuelas, Cristina Martínez-Oharriz, Juan M. Irache
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Online Access:https://doaj.org/article/b0e5b9bcfabe4ba4b626178dcae7dd37
Tags: Add Tag
No Tags, Be the first to tag this record!