A critical role for NF2 and the Hippo pathway in branching morphogenesis
Branching morphogenesis is essential for the formation of most epithelial organs. Here, the authors show that Neurofibromatosis 2 (NF2), the Hippo pathway kinases LATS1 and LATS2, and the transcriptional co-activators YAP and TAZ control tip identity, RET signalling and branching morphogenesis in th...
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Autores principales: | Antoine Reginensi, Leonie Enderle, Alex Gregorieff, Randy L. Johnson, Jeffrey L. Wrana, Helen McNeill |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/b0ee73c8d77b4a91869ff77ef701be43 |
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