CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3

Highlights 1. CircSETDB1 expression was increased in SOC tissues and cells. 2. CircSETDB1 silencing repressed the malignancy of SOC cells. 3. CircSETDB1 mediated SOC malignant progression by interacting with miR-129-3p. 4. MAP3K3 served as a target gene of miR-129-3p. 5. CircSETDB1 knockdown inhibit...

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Autores principales:	Bo Li, Lu Zhang
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	SOC circSETDB1 miR-129-3p MAP3K3 Gynecology and obstetrics RG1-991
Acceso en línea:	https://doaj.org/article/b0fb692d7fab44ccaf779d0d784c3dc1
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spelling	oai:doaj.org-article:b0fb692d7fab44ccaf779d0d784c3dc12021-11-21T12:32:05ZCircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K310.1186/s13048-021-00875-01757-2215https://doaj.org/article/b0fb692d7fab44ccaf779d0d784c3dc12021-11-01T00:00:00Zhttps://doi.org/10.1186/s13048-021-00875-0https://doaj.org/toc/1757-2215Highlights 1. CircSETDB1 expression was increased in SOC tissues and cells. 2. CircSETDB1 silencing repressed the malignancy of SOC cells. 3. CircSETDB1 mediated SOC malignant progression by interacting with miR-129-3p. 4. MAP3K3 served as a target gene of miR-129-3p. 5. CircSETDB1 knockdown inhibited tumor formation in vivo.Bo LiLu ZhangBMCarticleSOCcircSETDB1miR-129-3pMAP3K3Gynecology and obstetricsRG1-991ENJournal of Ovarian Research, Vol 14, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	SOC circSETDB1 miR-129-3p MAP3K3 Gynecology and obstetrics RG1-991
spellingShingle	SOC circSETDB1 miR-129-3p MAP3K3 Gynecology and obstetrics RG1-991 Bo Li Lu Zhang CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3
description	Highlights 1. CircSETDB1 expression was increased in SOC tissues and cells. 2. CircSETDB1 silencing repressed the malignancy of SOC cells. 3. CircSETDB1 mediated SOC malignant progression by interacting with miR-129-3p. 4. MAP3K3 served as a target gene of miR-129-3p. 5. CircSETDB1 knockdown inhibited tumor formation in vivo.
format	article
author	Bo Li Lu Zhang
author_facet	Bo Li Lu Zhang
author_sort	Bo Li
title	CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3
title_short	CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3
title_full	CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3
title_fullStr	CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3
title_full_unstemmed	CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3
title_sort	circsetdb1 knockdown inhibits the malignant progression of serous ovarian cancer through mir-129-3p-dependent regulation of map3k3
publisher	BMC
publishDate	2021
url	https://doaj.org/article/b0fb692d7fab44ccaf779d0d784c3dc1
work_keys_str_mv	AT boli circsetdb1knockdowninhibitsthemalignantprogressionofserousovariancancerthroughmir1293pdependentregulationofmap3k3 AT luzhang circsetdb1knockdowninhibitsthemalignantprogressionofserousovariancancerthroughmir1293pdependentregulationofmap3k3
_version_	1718418964299644928

CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3

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