Crystal structure of human METTL6, the m3C methyltransferase

Ran Chen et al. report the crystal structure of human m3C methyltrasfease METTL6. They generate structure models of hMETTL6 in complex with substrates, providing important insight into the molecular recognition mechanism by METTL6 and may aid in the METTL-based rational drug design in the future.

Saved in:
Bibliographic Details
Main Authors: Ran Chen, Jie Zhou, Ling Liu, Xue-Ling Mao, Xiaolong Zhou, Wei Xie
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Online Access:https://doaj.org/article/b0fe700029b24643a4a01b21bcf67940
Tags: Add Tag
No Tags, Be the first to tag this record!