Intracranial Involvement in Takayasu’s Arteritis

Takayasu’s arteritis (TAK) is a large-vessel vasculitis that targets the aorta and its major branches. Although extracranial vascular involvement is uniformly present in this disease, the frequency of intracranial involvement in TAK has not been well studied. We retrospectively reviewed the clinical...

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Autores principales:	Andrea Johnson, Derek Emery, Alison Clifford
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	Takayasu’s arteritis vasculitis intracranial stroke imaging Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/b103911b82124a198ac55053951887cf
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spelling	oai:doaj.org-article:b103911b82124a198ac55053951887cf2021-11-25T17:20:36ZIntracranial Involvement in Takayasu’s Arteritis10.3390/diagnostics111119972075-4418https://doaj.org/article/b103911b82124a198ac55053951887cf2021-10-01T00:00:00Zhttps://www.mdpi.com/2075-4418/11/11/1997https://doaj.org/toc/2075-4418Takayasu’s arteritis (TAK) is a large-vessel vasculitis that targets the aorta and its major branches. Although extracranial vascular involvement is uniformly present in this disease, the frequency of intracranial involvement in TAK has not been well studied. We retrospectively reviewed the clinical and imaging records of patients diagnosed with TAK at a single Canadian university medical centre to determine the prevalence of intracranial vascular involvement. Intracranial vascular and non-vascular findings were described, and a review of the literature was performed. Of 20 patients with TAK, 12 had vascular neuroimaging completed. Intracranial vascular lesions were identified in 4 patients (33.3% of those with imaging available, 20% of all patients). The frequency of intracranial vessel involvement in TAK may be more common than appreciated. Imaging of both the intra- and extra-cranial vessels should be considered in these young patients.Andrea JohnsonDerek EmeryAlison CliffordMDPI AGarticleTakayasu’s arteritisvasculitisintracranialstrokeimagingMedicine (General)R5-920ENDiagnostics, Vol 11, Iss 1997, p 1997 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Takayasu’s arteritis vasculitis intracranial stroke imaging Medicine (General) R5-920
spellingShingle	Takayasu’s arteritis vasculitis intracranial stroke imaging Medicine (General) R5-920 Andrea Johnson Derek Emery Alison Clifford Intracranial Involvement in Takayasu’s Arteritis
description	Takayasu’s arteritis (TAK) is a large-vessel vasculitis that targets the aorta and its major branches. Although extracranial vascular involvement is uniformly present in this disease, the frequency of intracranial involvement in TAK has not been well studied. We retrospectively reviewed the clinical and imaging records of patients diagnosed with TAK at a single Canadian university medical centre to determine the prevalence of intracranial vascular involvement. Intracranial vascular and non-vascular findings were described, and a review of the literature was performed. Of 20 patients with TAK, 12 had vascular neuroimaging completed. Intracranial vascular lesions were identified in 4 patients (33.3% of those with imaging available, 20% of all patients). The frequency of intracranial vessel involvement in TAK may be more common than appreciated. Imaging of both the intra- and extra-cranial vessels should be considered in these young patients.
format	article
author	Andrea Johnson Derek Emery Alison Clifford
author_facet	Andrea Johnson Derek Emery Alison Clifford
author_sort	Andrea Johnson
title	Intracranial Involvement in Takayasu’s Arteritis
title_short	Intracranial Involvement in Takayasu’s Arteritis
title_full	Intracranial Involvement in Takayasu’s Arteritis
title_fullStr	Intracranial Involvement in Takayasu’s Arteritis
title_full_unstemmed	Intracranial Involvement in Takayasu’s Arteritis
title_sort	intracranial involvement in takayasu’s arteritis
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/b103911b82124a198ac55053951887cf
work_keys_str_mv	AT andreajohnson intracranialinvolvementintakayasusarteritis AT derekemery intracranialinvolvementintakayasusarteritis AT alisonclifford intracranialinvolvementintakayasusarteritis
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Intracranial Involvement in Takayasu’s Arteritis

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