Massively parallel RNA device engineering in mammalian cells with RNA-Seq

Synthetic RNA-based devices can dynamically control a wide range of processes. Here the authors develop a quantitative and high-throughput mammalian cell-based RNA-seq assay to efficiently engineer ribozyme switches.

Guardado en:

Detalles Bibliográficos
Autores principales:	Joy S. Xiang, Matias Kaplan, Peter Dykstra, Michaela Hinks, Maureen McKeague, Christina D. Smolke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b1085f5500c446be9254e89e2d3669c0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b1085f5500c446be9254e89e2d3669c0
record_format	dspace
spelling	oai:doaj.org-article:b1085f5500c446be9254e89e2d3669c02021-12-02T17:01:32ZMassively parallel RNA device engineering in mammalian cells with RNA-Seq10.1038/s41467-019-12334-y2041-1723https://doaj.org/article/b1085f5500c446be9254e89e2d3669c02019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12334-yhttps://doaj.org/toc/2041-1723Synthetic RNA-based devices can dynamically control a wide range of processes. Here the authors develop a quantitative and high-throughput mammalian cell-based RNA-seq assay to efficiently engineer ribozyme switches.Joy S. XiangMatias KaplanPeter DykstraMichaela HinksMaureen McKeagueChristina D. SmolkeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Joy S. Xiang Matias Kaplan Peter Dykstra Michaela Hinks Maureen McKeague Christina D. Smolke Massively parallel RNA device engineering in mammalian cells with RNA-Seq
description	Synthetic RNA-based devices can dynamically control a wide range of processes. Here the authors develop a quantitative and high-throughput mammalian cell-based RNA-seq assay to efficiently engineer ribozyme switches.
format	article
author	Joy S. Xiang Matias Kaplan Peter Dykstra Michaela Hinks Maureen McKeague Christina D. Smolke
author_facet	Joy S. Xiang Matias Kaplan Peter Dykstra Michaela Hinks Maureen McKeague Christina D. Smolke
author_sort	Joy S. Xiang
title	Massively parallel RNA device engineering in mammalian cells with RNA-Seq
title_short	Massively parallel RNA device engineering in mammalian cells with RNA-Seq
title_full	Massively parallel RNA device engineering in mammalian cells with RNA-Seq
title_fullStr	Massively parallel RNA device engineering in mammalian cells with RNA-Seq
title_full_unstemmed	Massively parallel RNA device engineering in mammalian cells with RNA-Seq
title_sort	massively parallel rna device engineering in mammalian cells with rna-seq
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b1085f5500c446be9254e89e2d3669c0
work_keys_str_mv	AT joysxiang massivelyparallelrnadeviceengineeringinmammaliancellswithrnaseq AT matiaskaplan massivelyparallelrnadeviceengineeringinmammaliancellswithrnaseq AT peterdykstra massivelyparallelrnadeviceengineeringinmammaliancellswithrnaseq AT michaelahinks massivelyparallelrnadeviceengineeringinmammaliancellswithrnaseq AT maureenmckeague massivelyparallelrnadeviceengineeringinmammaliancellswithrnaseq AT christinadsmolke massivelyparallelrnadeviceengineeringinmammaliancellswithrnaseq
_version_	1718382106592149504

Massively parallel RNA device engineering in mammalian cells with RNA-Seq

Ejemplares similares