SEPSIS AT HIV-POSITIVE PATIENTS

Septic implications at patients aren’t a rarity, especially in surgical, pediatric and obstetric practice now. However not enough attention, despite epidemic of this disease is paid to implication of a sepsis at patients with HIV infection now. Clinical laboratory implications of a sepsis at 36 pati...

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Autores principales: L. V. Puzyryova, V. D. Konchenko, L. M. Dalabayeva
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Lenguaje:RU
Publicado: Sankt-Peterburg : NIIÈM imeni Pastera 2017
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Acceso en línea:https://doaj.org/article/b11071b20aa84575bc56278b95bd75a3
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spelling oai:doaj.org-article:b11071b20aa84575bc56278b95bd75a32021-11-22T07:09:48ZSEPSIS AT HIV-POSITIVE PATIENTS2220-76192313-739810.15789/2220-7619-2017-3-251-258https://doaj.org/article/b11071b20aa84575bc56278b95bd75a32017-09-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/557https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Septic implications at patients aren’t a rarity, especially in surgical, pediatric and obstetric practice now. However not enough attention, despite epidemic of this disease is paid to implication of a sepsis at patients with HIV infection now. Clinical laboratory implications of a sepsis at 36 patients with HIV infection are analysed. The main group is presented by patients with a lethal outcome (n = 18), control — with a positive outcome of a stationary stage of treatment (n = 18). Work is carried out on materials of the Infectious hospital No. 1 of D.M. Dalmatov of Omsk. At HIV-positive patients the stage of secondary diseases met most more often. Anti-retrovirus therapy was accepted only by 33% of patients in control group. At the died patients the hyperthermia arose after development of complaints from organs and systems and lasted less than 15 days. Low indicators of the CD4+ lymphocytes and a high virus load of HIV in a blood of patients with a lethal outcome became perceptible. In the general blood test thrombocytopenias, eosinopenias, monocytopenias, in the biochemical analysis — augmentation of the general bilirubin, thymol turbidity test, prothrombin ratio, urea were more often taped. At a bacteriological blood analysis various microflora with prevalence of S. aureus, sometimes in combination with Gram-negative flora was taped. Symptoms of an infectious endocarditis were taped at every second dead of the HIV-positive patient. Almost at all patients radiological changes in a pulmonary tissue were taped. Thus, clinical implications at patients with HIV infection are few symptoms and not typicalness that demands further studying.L. V. PuzyryovaV. D. KonchenkoL. M. DalabayevaSankt-Peterburg : NIIÈM imeni Pasteraarticlesepsishiv infectionimmunosupressiongram-positive sepsisgram-negative sepsisthrombocytopeniainfectious endocarditisInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 7, Iss 3, Pp 251-258 (2017)
institution DOAJ
collection DOAJ
language RU
topic sepsis
hiv infection
immunosupression
gram-positive sepsis
gram-negative sepsis
thrombocytopenia
infectious endocarditis
Infectious and parasitic diseases
RC109-216
spellingShingle sepsis
hiv infection
immunosupression
gram-positive sepsis
gram-negative sepsis
thrombocytopenia
infectious endocarditis
Infectious and parasitic diseases
RC109-216
L. V. Puzyryova
V. D. Konchenko
L. M. Dalabayeva
SEPSIS AT HIV-POSITIVE PATIENTS
description Septic implications at patients aren’t a rarity, especially in surgical, pediatric and obstetric practice now. However not enough attention, despite epidemic of this disease is paid to implication of a sepsis at patients with HIV infection now. Clinical laboratory implications of a sepsis at 36 patients with HIV infection are analysed. The main group is presented by patients with a lethal outcome (n = 18), control — with a positive outcome of a stationary stage of treatment (n = 18). Work is carried out on materials of the Infectious hospital No. 1 of D.M. Dalmatov of Omsk. At HIV-positive patients the stage of secondary diseases met most more often. Anti-retrovirus therapy was accepted only by 33% of patients in control group. At the died patients the hyperthermia arose after development of complaints from organs and systems and lasted less than 15 days. Low indicators of the CD4+ lymphocytes and a high virus load of HIV in a blood of patients with a lethal outcome became perceptible. In the general blood test thrombocytopenias, eosinopenias, monocytopenias, in the biochemical analysis — augmentation of the general bilirubin, thymol turbidity test, prothrombin ratio, urea were more often taped. At a bacteriological blood analysis various microflora with prevalence of S. aureus, sometimes in combination with Gram-negative flora was taped. Symptoms of an infectious endocarditis were taped at every second dead of the HIV-positive patient. Almost at all patients radiological changes in a pulmonary tissue were taped. Thus, clinical implications at patients with HIV infection are few symptoms and not typicalness that demands further studying.
format article
author L. V. Puzyryova
V. D. Konchenko
L. M. Dalabayeva
author_facet L. V. Puzyryova
V. D. Konchenko
L. M. Dalabayeva
author_sort L. V. Puzyryova
title SEPSIS AT HIV-POSITIVE PATIENTS
title_short SEPSIS AT HIV-POSITIVE PATIENTS
title_full SEPSIS AT HIV-POSITIVE PATIENTS
title_fullStr SEPSIS AT HIV-POSITIVE PATIENTS
title_full_unstemmed SEPSIS AT HIV-POSITIVE PATIENTS
title_sort sepsis at hiv-positive patients
publisher Sankt-Peterburg : NIIÈM imeni Pastera
publishDate 2017
url https://doaj.org/article/b11071b20aa84575bc56278b95bd75a3
work_keys_str_mv AT lvpuzyryova sepsisathivpositivepatients
AT vdkonchenko sepsisathivpositivepatients
AT lmdalabayeva sepsisathivpositivepatients
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