High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains

Abstract Circadian variability is driven by genetics and Diversity Outbred (DO) mice is a powerful tool for examining the genetics of complex traits because their high genetic and phenotypic diversity compared to conventional mouse crosses. The DO population combines the genetic diversity of eight f...

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Auteurs principaux: Sam-Moon Kim, Chelsea A. Vadnie, Vivek M. Philip, Leona H. Gagnon, Kodavali V. Chowdari, Elissa J. Chesler, Colleen A. McClung, Ryan W. Logan
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/b12b457980724ac89299756c29d2f1e8
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