A mathematical modelling framework for the regulation of intra-cellular OCT4 in human pluripotent stem cells.

A mathematical modelling framework for the regulation of intra-cellular OCT4 in human pluripotent stem cells.

Human pluripotent stem cells (hPSCs) have the potential to differentiate into all cell types, a property known as pluripotency. A deeper understanding of how pluripotency is regulated is required to assist in controlling pluripotency and differentiation trajectories experimentally. Mathematical mode...

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Autores principales: L E Wadkin, S Orozco-Fuentes, I Neganova, M Lako, N G Parker, A Shukurov
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b1313e2ba3fc47b88c00bf7c595e0340
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