A mathematical modelling framework for the regulation of intra-cellular OCT4 in human pluripotent stem cells.
Human pluripotent stem cells (hPSCs) have the potential to differentiate into all cell types, a property known as pluripotency. A deeper understanding of how pluripotency is regulated is required to assist in controlling pluripotency and differentiation trajectories experimentally. Mathematical mode...
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Main Authors: | L E Wadkin, S Orozco-Fuentes, I Neganova, M Lako, N G Parker, A Shukurov |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
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Online Access: | https://doaj.org/article/b1313e2ba3fc47b88c00bf7c595e0340 |
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