State of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1

The aim of study is to assess lipid peroxidation and antioxidant system in men with diabetes mellitus type 1. The objective of this study was to identify features of the lipid peroxidation-antioxidant defense system in men of reproductive age with diabetes mellitus type 1. 22 men with diabetes melli...

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Autores principales:	L. V. Belenkaya, L. F. Sholokhov, M. A. Darenskaya, I. M. Mikhalevich
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	diabetes mellitus type 1 men lipid peroxidation antioxidant protection Science Q
Acceso en línea:	https://doaj.org/article/b13153900b7741e48777fbc10f6626ab
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spelling	oai:doaj.org-article:b13153900b7741e48777fbc10f6626ab2021-11-23T06:14:34ZState of lipid peroxidation - antioxidant system in men with diabetes mellitus type 12541-94202587-959610.12737/article_590823a40a10b5.33824132https://doaj.org/article/b13153900b7741e48777fbc10f6626ab2016-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/177https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The aim of study is to assess lipid peroxidation and antioxidant system in men with diabetes mellitus type 1. The objective of this study was to identify features of the lipid peroxidation-antioxidant defense system in men of reproductive age with diabetes mellitus type 1. 22 men with diabetes mellitus type 1 (the average age of 27.1 ± 7.38years) and30 healthy men of the same age (control group) (the average age of 28.0 ± 4.3 years) were involved in the study. The main and control groups were formed on the principle of "copy - pair". Standard clinical examination methods were used: history taking, physical examination and consultation of specialists to identify complications of diabetes. To determine the indicators of the system of free-radical lipid oxidation and activity of antioxidant protection, the spectrophotometric and fluorometric methods were used. In men with diabetes mellitus 1 type, there is increase in the level of active products reacting with thiobarbituric acid compared to the same indicator in the control group. The level of antioxidant protection in men with diabetes mellitus 1 type unlike the control was characterized by decrease in total antioxidant activity. However, stability of processes of superoxide dismutase activity and the glutathione system in comparison with control is observed against the backdrop of intensity increase of oxidative processes. Activation of lipid peroxidation is observed in men with diabetes mellitus type 1.L. V. BelenkayaL. F. SholokhovM. A. DarenskayaI. M. MikhalevichScientific Сentre for Family Health and Human Reproduction Problemsarticlediabetes mellitus type 1menlipid peroxidationantioxidant protectionScienceQRUActa Biomedica Scientifica, Vol 1, Iss 3(2), Pp 12-15 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	diabetes mellitus type 1 men lipid peroxidation antioxidant protection Science Q
spellingShingle	diabetes mellitus type 1 men lipid peroxidation antioxidant protection Science Q L. V. Belenkaya L. F. Sholokhov M. A. Darenskaya I. M. Mikhalevich State of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1
description	The aim of study is to assess lipid peroxidation and antioxidant system in men with diabetes mellitus type 1. The objective of this study was to identify features of the lipid peroxidation-antioxidant defense system in men of reproductive age with diabetes mellitus type 1. 22 men with diabetes mellitus type 1 (the average age of 27.1 ± 7.38years) and30 healthy men of the same age (control group) (the average age of 28.0 ± 4.3 years) were involved in the study. The main and control groups were formed on the principle of "copy - pair". Standard clinical examination methods were used: history taking, physical examination and consultation of specialists to identify complications of diabetes. To determine the indicators of the system of free-radical lipid oxidation and activity of antioxidant protection, the spectrophotometric and fluorometric methods were used. In men with diabetes mellitus 1 type, there is increase in the level of active products reacting with thiobarbituric acid compared to the same indicator in the control group. The level of antioxidant protection in men with diabetes mellitus 1 type unlike the control was characterized by decrease in total antioxidant activity. However, stability of processes of superoxide dismutase activity and the glutathione system in comparison with control is observed against the backdrop of intensity increase of oxidative processes. Activation of lipid peroxidation is observed in men with diabetes mellitus type 1.
format	article
author	L. V. Belenkaya L. F. Sholokhov M. A. Darenskaya I. M. Mikhalevich
author_facet	L. V. Belenkaya L. F. Sholokhov M. A. Darenskaya I. M. Mikhalevich
author_sort	L. V. Belenkaya
title	State of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1
title_short	State of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1
title_full	State of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1
title_fullStr	State of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1
title_full_unstemmed	State of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1
title_sort	state of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/b13153900b7741e48777fbc10f6626ab
work_keys_str_mv	AT lvbelenkaya stateoflipidperoxidationantioxidantsysteminmenwithdiabetesmellitustype1 AT lfsholokhov stateoflipidperoxidationantioxidantsysteminmenwithdiabetesmellitustype1 AT madarenskaya stateoflipidperoxidationantioxidantsysteminmenwithdiabetesmellitustype1 AT immikhalevich stateoflipidperoxidationantioxidantsysteminmenwithdiabetesmellitustype1
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State of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1

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