Modulation of Hoogsteen dynamics on DNA recognition

DNA is found in a dynamic equilibrium between standard Watson-Crick (WC) base pairs and non-standard Hoogsteen (HG) base pairs. Here the authors describe the influence of echinomycin and actinomycin D ligands binding on the HG-WC base pair dynamics in DNA.

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Autores principales:	Yu Xu, James McSally, Ioan Andricioaei, Hashim M. Al-Hashimi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b13b41ea233f4bdb8b17d86942bc33d6
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spelling	oai:doaj.org-article:b13b41ea233f4bdb8b17d86942bc33d62021-12-02T14:39:06ZModulation of Hoogsteen dynamics on DNA recognition10.1038/s41467-018-03516-12041-1723https://doaj.org/article/b13b41ea233f4bdb8b17d86942bc33d62018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03516-1https://doaj.org/toc/2041-1723DNA is found in a dynamic equilibrium between standard Watson-Crick (WC) base pairs and non-standard Hoogsteen (HG) base pairs. Here the authors describe the influence of echinomycin and actinomycin D ligands binding on the HG-WC base pair dynamics in DNA.Yu XuJames McSallyIoan AndricioaeiHashim M. Al-HashimiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yu Xu James McSally Ioan Andricioaei Hashim M. Al-Hashimi Modulation of Hoogsteen dynamics on DNA recognition
description	DNA is found in a dynamic equilibrium between standard Watson-Crick (WC) base pairs and non-standard Hoogsteen (HG) base pairs. Here the authors describe the influence of echinomycin and actinomycin D ligands binding on the HG-WC base pair dynamics in DNA.
format	article
author	Yu Xu James McSally Ioan Andricioaei Hashim M. Al-Hashimi
author_facet	Yu Xu James McSally Ioan Andricioaei Hashim M. Al-Hashimi
author_sort	Yu Xu
title	Modulation of Hoogsteen dynamics on DNA recognition
title_short	Modulation of Hoogsteen dynamics on DNA recognition
title_full	Modulation of Hoogsteen dynamics on DNA recognition
title_fullStr	Modulation of Hoogsteen dynamics on DNA recognition
title_full_unstemmed	Modulation of Hoogsteen dynamics on DNA recognition
title_sort	modulation of hoogsteen dynamics on dna recognition
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b13b41ea233f4bdb8b17d86942bc33d6
work_keys_str_mv	AT yuxu modulationofhoogsteendynamicsondnarecognition AT jamesmcsally modulationofhoogsteendynamicsondnarecognition AT ioanandricioaei modulationofhoogsteendynamicsondnarecognition AT hashimmalhashimi modulationofhoogsteendynamicsondnarecognition
_version_	1718390732986777600

Modulation of Hoogsteen dynamics on DNA recognition

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