LncRNA NNT-AS1 regulates proliferation, ECM accumulation and inflammation of human mesangial cells induced by high glucose through miR-214-5p/smad4
Highlights 1. Up-regulated levels of NNT-AS1 and smad4 in DN samples and HGMCs was manifested. 2. Potential binding sites of NNT-AS1 showed miR-214-5p as its direct target and NNT-AS1 as potential absorber for this microRNA, in turn increasing the expression of transcription factor smad4. 3. The res...
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| Auteurs principaux: | , , , , , , |
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| Format: | article |
| Langue: | EN |
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BMC
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/b13bea3225db40acb3b04d6e63e7588f |
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