Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages

Syphilis is caused by the bacterium Treponema pallidum subspecies pallidum (TPA), and incidence has risen recently in many countries. Here, Beale et al. provide whole-genome TPA sequences from 73 clinical samples and show how antimicrobial resistance emerged independently in circulating lineages.

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Autores principales:	Mathew A. Beale, Michael Marks, Sharon K. Sahi, Lauren C. Tantalo, Achyuta V. Nori, Patrick French, Sheila A. Lukehart, Christina M. Marra, Nicholas R. Thomson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b13df3c0a3d5427380e8c0a9049a22a1
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spelling	oai:doaj.org-article:b13df3c0a3d5427380e8c0a9049a22a12021-12-02T14:40:17ZGenomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages10.1038/s41467-019-11216-72041-1723https://doaj.org/article/b13df3c0a3d5427380e8c0a9049a22a12019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11216-7https://doaj.org/toc/2041-1723Syphilis is caused by the bacterium Treponema pallidum subspecies pallidum (TPA), and incidence has risen recently in many countries. Here, Beale et al. provide whole-genome TPA sequences from 73 clinical samples and show how antimicrobial resistance emerged independently in circulating lineages.Mathew A. BealeMichael MarksSharon K. SahiLauren C. TantaloAchyuta V. NoriPatrick FrenchSheila A. LukehartChristina M. MarraNicholas R. ThomsonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mathew A. Beale Michael Marks Sharon K. Sahi Lauren C. Tantalo Achyuta V. Nori Patrick French Sheila A. Lukehart Christina M. Marra Nicholas R. Thomson Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages
description	Syphilis is caused by the bacterium Treponema pallidum subspecies pallidum (TPA), and incidence has risen recently in many countries. Here, Beale et al. provide whole-genome TPA sequences from 73 clinical samples and show how antimicrobial resistance emerged independently in circulating lineages.
format	article
author	Mathew A. Beale Michael Marks Sharon K. Sahi Lauren C. Tantalo Achyuta V. Nori Patrick French Sheila A. Lukehart Christina M. Marra Nicholas R. Thomson
author_facet	Mathew A. Beale Michael Marks Sharon K. Sahi Lauren C. Tantalo Achyuta V. Nori Patrick French Sheila A. Lukehart Christina M. Marra Nicholas R. Thomson
author_sort	Mathew A. Beale
title	Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages
title_short	Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages
title_full	Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages
title_fullStr	Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages
title_full_unstemmed	Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages
title_sort	genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b13df3c0a3d5427380e8c0a9049a22a1
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Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages

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