Dysregulated transcriptional responses to SARS-CoV-2 in the periphery

The systemic immune features that distinguish COVID-19 from common infections remain incompletely elucidated. Here McClain et al. compare RNA sequencing in peripheral blood between subjects with SARS-CoV-2 and other respiratory infections and demonstrate dysregulated immune responses in COVID-19 wit...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Micah T. McClain, Florica J. Constantine, Ricardo Henao, Yiling Liu, Ephraim L. Tsalik, Thomas W. Burke, Julie M. Steinbrink, Elizabeth Petzold, Bradly P. Nicholson, Robert Rolfe, Bryan D. Kraft, Matthew S. Kelly, Daniel R. Saban, Chen Yu, Xiling Shen, Emily M. Ko, Gregory D. Sempowski, Thomas N. Denny, Geoffrey S. Ginsburg, Christopher W. Woods
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b140cf38382d49ca96a5aa166526b245
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b140cf38382d49ca96a5aa166526b245
record_format	dspace
spelling	oai:doaj.org-article:b140cf38382d49ca96a5aa166526b2452021-12-02T14:03:51ZDysregulated transcriptional responses to SARS-CoV-2 in the periphery10.1038/s41467-021-21289-y2041-1723https://doaj.org/article/b140cf38382d49ca96a5aa166526b2452021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21289-yhttps://doaj.org/toc/2041-1723The systemic immune features that distinguish COVID-19 from common infections remain incompletely elucidated. Here McClain et al. compare RNA sequencing in peripheral blood between subjects with SARS-CoV-2 and other respiratory infections and demonstrate dysregulated immune responses in COVID-19 with both heterogeneous and conserved components.Micah T. McClainFlorica J. ConstantineRicardo HenaoYiling LiuEphraim L. TsalikThomas W. BurkeJulie M. SteinbrinkElizabeth PetzoldBradly P. NicholsonRobert RolfeBryan D. KraftMatthew S. KellyDaniel R. SabanChen YuXiling ShenEmily M. KoGregory D. SempowskiThomas N. DennyGeoffrey S. GinsburgChristopher W. WoodsNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Micah T. McClain Florica J. Constantine Ricardo Henao Yiling Liu Ephraim L. Tsalik Thomas W. Burke Julie M. Steinbrink Elizabeth Petzold Bradly P. Nicholson Robert Rolfe Bryan D. Kraft Matthew S. Kelly Daniel R. Saban Chen Yu Xiling Shen Emily M. Ko Gregory D. Sempowski Thomas N. Denny Geoffrey S. Ginsburg Christopher W. Woods Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
description	The systemic immune features that distinguish COVID-19 from common infections remain incompletely elucidated. Here McClain et al. compare RNA sequencing in peripheral blood between subjects with SARS-CoV-2 and other respiratory infections and demonstrate dysregulated immune responses in COVID-19 with both heterogeneous and conserved components.
format	article
author	Micah T. McClain Florica J. Constantine Ricardo Henao Yiling Liu Ephraim L. Tsalik Thomas W. Burke Julie M. Steinbrink Elizabeth Petzold Bradly P. Nicholson Robert Rolfe Bryan D. Kraft Matthew S. Kelly Daniel R. Saban Chen Yu Xiling Shen Emily M. Ko Gregory D. Sempowski Thomas N. Denny Geoffrey S. Ginsburg Christopher W. Woods
author_facet	Micah T. McClain Florica J. Constantine Ricardo Henao Yiling Liu Ephraim L. Tsalik Thomas W. Burke Julie M. Steinbrink Elizabeth Petzold Bradly P. Nicholson Robert Rolfe Bryan D. Kraft Matthew S. Kelly Daniel R. Saban Chen Yu Xiling Shen Emily M. Ko Gregory D. Sempowski Thomas N. Denny Geoffrey S. Ginsburg Christopher W. Woods
author_sort	Micah T. McClain
title	Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
title_short	Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
title_full	Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
title_fullStr	Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
title_full_unstemmed	Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
title_sort	dysregulated transcriptional responses to sars-cov-2 in the periphery
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b140cf38382d49ca96a5aa166526b245
work_keys_str_mv	AT micahtmcclain dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT floricajconstantine dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT ricardohenao dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT yilingliu dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT ephraimltsalik dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT thomaswburke dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT juliemsteinbrink dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT elizabethpetzold dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT bradlypnicholson dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT robertrolfe dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT bryandkraft dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT matthewskelly dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT danielrsaban dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT chenyu dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT xilingshen dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT emilymko dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT gregorydsempowski dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT thomasndenny dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT geoffreysginsburg dysregulatedtranscriptionalresponsestosarscov2intheperiphery AT christopherwwoods dysregulatedtranscriptionalresponsestosarscov2intheperiphery
_version_	1718392102445907968

Dysregulated transcriptional responses to SARS-CoV-2 in the periphery

Ejemplares similares