Negative symptoms and speech pauses in youths at clinical high risk for psychosis

Abstract Aberrant pauses are characteristic of schizophrenia and are robustly associated with its negative symptoms. Here, we found that pause behavior was associated with negative symptoms in individuals at clinical high risk (CHR) for psychosis, and with measures of syntactic complexity—phrase len...

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Autores principales:	Emma R. Stanislawski, Zarina R. Bilgrami, Cansu Sarac, Sahil Garg, Stephen Heisig, Guillermo A. Cecchi, Carla Agurto, Cheryl M. Corcoran
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Psychiatry RC435-571
Acceso en línea:	https://doaj.org/article/b142810868eb45109f3b12a696219cd1
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spelling	oai:doaj.org-article:b142810868eb45109f3b12a696219cd12021-12-02T13:48:52ZNegative symptoms and speech pauses in youths at clinical high risk for psychosis10.1038/s41537-020-00132-12334-265Xhttps://doaj.org/article/b142810868eb45109f3b12a696219cd12021-01-01T00:00:00Zhttps://doi.org/10.1038/s41537-020-00132-1https://doaj.org/toc/2334-265XAbstract Aberrant pauses are characteristic of schizophrenia and are robustly associated with its negative symptoms. Here, we found that pause behavior was associated with negative symptoms in individuals at clinical high risk (CHR) for psychosis, and with measures of syntactic complexity—phrase length and usage of determiners that introduce clauses—that we previously showed in this same CHR cohort to help comprise a classifier that predicted psychosis. These findings suggest a common impairment in discourse planning and verbal self-monitoring that affects both speech and language, and which is detected in clinical ratings of negative symptoms.Emma R. StanislawskiZarina R. BilgramiCansu SaracSahil GargStephen HeisigGuillermo A. CecchiCarla AgurtoCheryl M. CorcoranNature PortfolioarticlePsychiatryRC435-571ENnpj Schizophrenia, Vol 7, Iss 1, Pp 1-3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Psychiatry RC435-571
spellingShingle	Psychiatry RC435-571 Emma R. Stanislawski Zarina R. Bilgrami Cansu Sarac Sahil Garg Stephen Heisig Guillermo A. Cecchi Carla Agurto Cheryl M. Corcoran Negative symptoms and speech pauses in youths at clinical high risk for psychosis
description	Abstract Aberrant pauses are characteristic of schizophrenia and are robustly associated with its negative symptoms. Here, we found that pause behavior was associated with negative symptoms in individuals at clinical high risk (CHR) for psychosis, and with measures of syntactic complexity—phrase length and usage of determiners that introduce clauses—that we previously showed in this same CHR cohort to help comprise a classifier that predicted psychosis. These findings suggest a common impairment in discourse planning and verbal self-monitoring that affects both speech and language, and which is detected in clinical ratings of negative symptoms.
format	article
author	Emma R. Stanislawski Zarina R. Bilgrami Cansu Sarac Sahil Garg Stephen Heisig Guillermo A. Cecchi Carla Agurto Cheryl M. Corcoran
author_facet	Emma R. Stanislawski Zarina R. Bilgrami Cansu Sarac Sahil Garg Stephen Heisig Guillermo A. Cecchi Carla Agurto Cheryl M. Corcoran
author_sort	Emma R. Stanislawski
title	Negative symptoms and speech pauses in youths at clinical high risk for psychosis
title_short	Negative symptoms and speech pauses in youths at clinical high risk for psychosis
title_full	Negative symptoms and speech pauses in youths at clinical high risk for psychosis
title_fullStr	Negative symptoms and speech pauses in youths at clinical high risk for psychosis
title_full_unstemmed	Negative symptoms and speech pauses in youths at clinical high risk for psychosis
title_sort	negative symptoms and speech pauses in youths at clinical high risk for psychosis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b142810868eb45109f3b12a696219cd1
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Negative symptoms and speech pauses in youths at clinical high risk for psychosis

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