Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification
Ubiquitylation and SUMOylation are two important related post-translational modifications. Here the authors present an approach for the simultaneous identification and quantification of protein-wide SUMO and ubiquitin sites from a single sample, uncovering widespread crosstalk between the two modifi...
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Nature Portfolio
2017
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oai:doaj.org-article:b154cff5cc4243dfbe1fb2ed128260a02021-12-02T15:38:51ZUncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification10.1038/ncomms141092041-1723https://doaj.org/article/b154cff5cc4243dfbe1fb2ed128260a02017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14109https://doaj.org/toc/2041-1723Ubiquitylation and SUMOylation are two important related post-translational modifications. Here the authors present an approach for the simultaneous identification and quantification of protein-wide SUMO and ubiquitin sites from a single sample, uncovering widespread crosstalk between the two modifications.Frédéric LamoliatteFrancis P. McManusGhizlane MaarifiMounira K. Chelbi-AlixPierre ThibaultNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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Science Q Frédéric Lamoliatte Francis P. McManus Ghizlane Maarifi Mounira K. Chelbi-Alix Pierre Thibault Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification |
description |
Ubiquitylation and SUMOylation are two important related post-translational modifications. Here the authors present an approach for the simultaneous identification and quantification of protein-wide SUMO and ubiquitin sites from a single sample, uncovering widespread crosstalk between the two modifications. |
format |
article |
author |
Frédéric Lamoliatte Francis P. McManus Ghizlane Maarifi Mounira K. Chelbi-Alix Pierre Thibault |
author_facet |
Frédéric Lamoliatte Francis P. McManus Ghizlane Maarifi Mounira K. Chelbi-Alix Pierre Thibault |
author_sort |
Frédéric Lamoliatte |
title |
Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification |
title_short |
Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification |
title_full |
Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification |
title_fullStr |
Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification |
title_full_unstemmed |
Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification |
title_sort |
uncovering the sumoylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/b154cff5cc4243dfbe1fb2ed128260a0 |
work_keys_str_mv |
AT fredericlamoliatte uncoveringthesumoylationandubiquitylationcrosstalkinhumancellsusingsequentialpeptideimmunopurification AT francispmcmanus uncoveringthesumoylationandubiquitylationcrosstalkinhumancellsusingsequentialpeptideimmunopurification AT ghizlanemaarifi uncoveringthesumoylationandubiquitylationcrosstalkinhumancellsusingsequentialpeptideimmunopurification AT mounirakchelbialix uncoveringthesumoylationandubiquitylationcrosstalkinhumancellsusingsequentialpeptideimmunopurification AT pierrethibault uncoveringthesumoylationandubiquitylationcrosstalkinhumancellsusingsequentialpeptideimmunopurification |
_version_ |
1718386068520173568 |