A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors

False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.

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Detalles Bibliográficos
Autores principales: Rabia Mateen, M. Monsur Ali, Todd Hoare
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/b15875df484545e4be2b90b2fc1c4eda
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Descripción
Sumario:False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.