A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors

False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.

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Detalles Bibliográficos
Autores principales:	Rabia Mateen, M. Monsur Ali, Todd Hoare
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b15875df484545e4be2b90b2fc1c4eda
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spelling	oai:doaj.org-article:b15875df484545e4be2b90b2fc1c4eda2021-12-02T17:33:05ZA printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors10.1038/s41467-018-02956-z2041-1723https://doaj.org/article/b15875df484545e4be2b90b2fc1c4eda2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02956-zhttps://doaj.org/toc/2041-1723False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.Rabia MateenM. Monsur AliTodd HoareNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rabia Mateen M. Monsur Ali Todd Hoare A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
description	False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.
format	article
author	Rabia Mateen M. Monsur Ali Todd Hoare
author_facet	Rabia Mateen M. Monsur Ali Todd Hoare
author_sort	Rabia Mateen
title	A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
title_short	A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
title_full	A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
title_fullStr	A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
title_full_unstemmed	A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
title_sort	printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b15875df484545e4be2b90b2fc1c4eda
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A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors

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