Carbamoyl phosphate and its substitutes for the uracil synthesis in origins of life scenarios

Abstract The first step of pyrimidine synthesis along the orotate pathway is studied to test the hypothesis of geochemical continuity of protometabolic pathways at the origins of life. Carbamoyl phosphate (CP) is the first high-energy building block that intervenes in the in vivo synthesis of the ur...

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Autores principales: Louis M. P. Ter-Ovanessian, Baptiste Rigaud, Alberto Mezzetti, Jean-François Lambert, Marie-Christine Maurel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b15ae8f9ad70435382ae8a9240e4c989
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