Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders

Introduction: Chemosensory disorders have been identified as typical symptoms of COVID-19. Objective: To characterize patients with COVID-19 and referred chemosensory disorders. Methods: 152 hospitalized patients, positive for COVID-19, with referred chemosensory disorders were included. Clinical an...

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Autores principales:	Sergio César Lorenzo González, Elizabeth Proenza Ramírez, José Adrián Romero García, Yosvanis Leyva Zamora, Alexánder Fernández Zaldívar
Formato:	article
Lenguaje:	ES
Publicado:	ECIMED 2021
Materias:	covid-19 sars-cov-2 trastornos del olfato trastornos del gusto anosmia ageusia. Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/b16420f126724370b2cd00f7f863cab8
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spelling	oai:doaj.org-article:b16420f126724370b2cd00f7f863cab82021-11-30T13:31:08ZClinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders1561-3046https://doaj.org/article/b16420f126724370b2cd00f7f863cab82021-11-01T00:00:00Zhttp://www.revmedmilitar.sld.cu/index.php/mil/article/view/1526https://doaj.org/toc/1561-3046Introduction: Chemosensory disorders have been identified as typical symptoms of COVID-19. Objective: To characterize patients with COVID-19 and referred chemosensory disorders. Methods: 152 hospitalized patients, positive for COVID-19, with referred chemosensory disorders were included. Clinical and epidemiological variables, inflammation markers, chest X-ray and treatment used were studied. Results: The average age was 40.2 years, the female sex 59.2% and the antecedent prevailed, confirmed case contact (62.5%), with anosmia (95.7%), ageusia (93.3%), without comorbidities (53.3%) and absence of accompanying symptoms (36.8%). In patients with an indeterminate source of infection, confirmation was late (3.89 days); there were no significant differences between those who presented one or both disorders (p = 0.053), nor between those who did or did not present associated symptoms (p = 0.14). In 2% the neutrophil index was greater than 4; 3.3% had an absolute lymphocyte count lower than 1500x106/L and 68.4% did not show radiological alteration. 5.9% required antimicrobials and 5.3% immunomodulators; 1.3% were admitted to intensive care. Most (95.4%) were discharged from the clinic and 1.3% died. Conclusions: The female sex predominates, with ageusia or anosmia; those who do not have an epidemiological history are diagnosed with delay. There are no differences in seeking care, for one or both disorders, or for accompanying symptoms. They refer more in the absence of complications and serious pictures. Those who refer them spontaneously are generally healthy and oligosymptomatic people.Sergio César Lorenzo GonzálezElizabeth Proenza RamírezJosé Adrián Romero GarcíaYosvanis Leyva ZamoraAlexánder Fernández ZaldívarECIMEDarticlecovid-19sars-cov-2trastornos del olfatotrastornos del gustoanosmiaageusia.MedicineRMedicine (General)R5-920ESRevista Cubana de Medicina Militar, Vol 50, Iss 4, Pp e02101526-e02101526 (2021)
institution	DOAJ
collection	DOAJ
language	ES
topic	covid-19 sars-cov-2 trastornos del olfato trastornos del gusto anosmia ageusia. Medicine R Medicine (General) R5-920
spellingShingle	covid-19 sars-cov-2 trastornos del olfato trastornos del gusto anosmia ageusia. Medicine R Medicine (General) R5-920 Sergio César Lorenzo González Elizabeth Proenza Ramírez José Adrián Romero García Yosvanis Leyva Zamora Alexánder Fernández Zaldívar Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
description	Introduction: Chemosensory disorders have been identified as typical symptoms of COVID-19. Objective: To characterize patients with COVID-19 and referred chemosensory disorders. Methods: 152 hospitalized patients, positive for COVID-19, with referred chemosensory disorders were included. Clinical and epidemiological variables, inflammation markers, chest X-ray and treatment used were studied. Results: The average age was 40.2 years, the female sex 59.2% and the antecedent prevailed, confirmed case contact (62.5%), with anosmia (95.7%), ageusia (93.3%), without comorbidities (53.3%) and absence of accompanying symptoms (36.8%). In patients with an indeterminate source of infection, confirmation was late (3.89 days); there were no significant differences between those who presented one or both disorders (p = 0.053), nor between those who did or did not present associated symptoms (p = 0.14). In 2% the neutrophil index was greater than 4; 3.3% had an absolute lymphocyte count lower than 1500x106/L and 68.4% did not show radiological alteration. 5.9% required antimicrobials and 5.3% immunomodulators; 1.3% were admitted to intensive care. Most (95.4%) were discharged from the clinic and 1.3% died. Conclusions: The female sex predominates, with ageusia or anosmia; those who do not have an epidemiological history are diagnosed with delay. There are no differences in seeking care, for one or both disorders, or for accompanying symptoms. They refer more in the absence of complications and serious pictures. Those who refer them spontaneously are generally healthy and oligosymptomatic people.
format	article
author	Sergio César Lorenzo González Elizabeth Proenza Ramírez José Adrián Romero García Yosvanis Leyva Zamora Alexánder Fernández Zaldívar
author_facet	Sergio César Lorenzo González Elizabeth Proenza Ramírez José Adrián Romero García Yosvanis Leyva Zamora Alexánder Fernández Zaldívar
author_sort	Sergio César Lorenzo González
title	Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
title_short	Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
title_full	Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
title_fullStr	Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
title_full_unstemmed	Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
title_sort	clinical and epidemiological characteristics of covid-19 patients with chemosensory disorders
publisher	ECIMED
publishDate	2021
url	https://doaj.org/article/b16420f126724370b2cd00f7f863cab8
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Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders

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