Trivial and nontrivial error sources account for misidentification of protein partners in mutual information approaches

Abstract The problem of finding the correct set of partners for a given pair of interacting protein families based on multi-sequence alignments (MSAs) has received great attention over the years. Recently, the native contacts of two interacting proteins were shown to store the strongest mutual infor...

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Bibliographic Details
Main Authors: Camila Pontes, Miguel Andrade, José Fiorote, Werner Treptow
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/b166faf4fe6a45e08cccaab513bd19d5
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