Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis

Optogenetics is opening the possibility to not only perturb morphogenesis, but also to guide it. Here, the authors use this technique to reconstruct epithelial folding in Drosophila embryos and study the relationship between strength of Rho activation, apical constrictions, and tissue invagination.

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Detalles Bibliográficos
Autores principales: Emiliano Izquierdo, Theresa Quinkler, Stefano De Renzis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/b1741e13a0c346a59adb26660f00092b
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Sumario:Optogenetics is opening the possibility to not only perturb morphogenesis, but also to guide it. Here, the authors use this technique to reconstruct epithelial folding in Drosophila embryos and study the relationship between strength of Rho activation, apical constrictions, and tissue invagination.