Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis

Optogenetics is opening the possibility to not only perturb morphogenesis, but also to guide it. Here, the authors use this technique to reconstruct epithelial folding in Drosophila embryos and study the relationship between strength of Rho activation, apical constrictions, and tissue invagination.

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Autores principales:	Emiliano Izquierdo, Theresa Quinkler, Stefano De Renzis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b1741e13a0c346a59adb26660f00092b
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spelling	oai:doaj.org-article:b1741e13a0c346a59adb26660f00092b2021-12-02T15:34:15ZGuided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis10.1038/s41467-018-04754-z2041-1723https://doaj.org/article/b1741e13a0c346a59adb26660f00092b2018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04754-zhttps://doaj.org/toc/2041-1723Optogenetics is opening the possibility to not only perturb morphogenesis, but also to guide it. Here, the authors use this technique to reconstruct epithelial folding in Drosophila embryos and study the relationship between strength of Rho activation, apical constrictions, and tissue invagination.Emiliano IzquierdoTheresa QuinklerStefano De RenzisNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Emiliano Izquierdo Theresa Quinkler Stefano De Renzis Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
description	Optogenetics is opening the possibility to not only perturb morphogenesis, but also to guide it. Here, the authors use this technique to reconstruct epithelial folding in Drosophila embryos and study the relationship between strength of Rho activation, apical constrictions, and tissue invagination.
format	article
author	Emiliano Izquierdo Theresa Quinkler Stefano De Renzis
author_facet	Emiliano Izquierdo Theresa Quinkler Stefano De Renzis
author_sort	Emiliano Izquierdo
title	Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
title_short	Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
title_full	Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
title_fullStr	Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
title_full_unstemmed	Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
title_sort	guided morphogenesis through optogenetic activation of rho signalling during early drosophila embryogenesis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b1741e13a0c346a59adb26660f00092b
work_keys_str_mv	AT emilianoizquierdo guidedmorphogenesisthroughoptogeneticactivationofrhosignallingduringearlydrosophilaembryogenesis AT theresaquinkler guidedmorphogenesisthroughoptogeneticactivationofrhosignallingduringearlydrosophilaembryogenesis AT stefanoderenzis guidedmorphogenesisthroughoptogeneticactivationofrhosignallingduringearlydrosophilaembryogenesis
_version_	1718386921876488192

Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis

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