EFFICIENCY OF SOME IMMUNOMODULATORY DRUGS FOR PREVENTION OF RESPIRATORY INFECTIONS AND THEIR COMPLICATIONS IN YOUNG SCHOOLCHILDREN WITH RECURRENT RESPIRATORY INFECTIONS

Abstract. We performed a study of efficiency for various immunocorrective drugs in a group of 548 young schoolchildren with recurrent respiratory infections. Frequency of respiratory infections and complication rates were taken as endpoints in this study. It was revealed, that preventive immunocorre...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	R. V. Maiorov, M. V. Chereshneva, S. D. Verzilin, V. A. Chereshnev
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	recurrent respiratory diseases children immunomodulatory therapy Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/b17b7434178f456bb9f71807cd1aec17
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b17b7434178f456bb9f71807cd1aec17
record_format	dspace
spelling	oai:doaj.org-article:b17b7434178f456bb9f71807cd1aec172021-11-18T08:03:43ZEFFICIENCY OF SOME IMMUNOMODULATORY DRUGS FOR PREVENTION OF RESPIRATORY INFECTIONS AND THEIR COMPLICATIONS IN YOUNG SCHOOLCHILDREN WITH RECURRENT RESPIRATORY INFECTIONS1563-06252313-741X10.15789/1563-0625-2013-3-255-262https://doaj.org/article/b17b7434178f456bb9f71807cd1aec172014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/629https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We performed a study of efficiency for various immunocorrective drugs in a group of 548 young schoolchildren with recurrent respiratory infections. Frequency of respiratory infections and complication rates were taken as endpoints in this study. It was revealed, that preventive immunocorrection by bacterial lysates or glucosamine muramildipeptide combined with vitamin-mineral complexes may reduce frequency of respiratory infections and their complications at statistically significant levels, as well as to restore some abnormal parameters of immune profile, i.e., CD3, CD4, CD16, induced NBT test, IFNγ, TNFα and IgG. Preventive use of Echinaceae purpurae herbae succus or interferon alpha-2b in combination with vitaminmineral complexes statistically significantly reduces only the frequency of respiratory infections, and partially restores some deficient parameters of immune status (IgG, TNFα, CD16). Introduction of preventive immunocorrection in childhood institutions, with > 90 % coverage of children with recurrent respiratory diseases is associated with a decrease in frequency of respiratory infections not only in this cohort, like as among general population of the same age group.R. V. MaiorovM. V. ChereshnevaS. D. VerzilinV. A. ChereshnevSPb RAACIarticlerecurrent respiratory diseaseschildrenimmunomodulatory therapyImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 15, Iss 3, Pp 255-262 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	recurrent respiratory diseases children immunomodulatory therapy Immunologic diseases. Allergy RC581-607
spellingShingle	recurrent respiratory diseases children immunomodulatory therapy Immunologic diseases. Allergy RC581-607 R. V. Maiorov M. V. Chereshneva S. D. Verzilin V. A. Chereshnev EFFICIENCY OF SOME IMMUNOMODULATORY DRUGS FOR PREVENTION OF RESPIRATORY INFECTIONS AND THEIR COMPLICATIONS IN YOUNG SCHOOLCHILDREN WITH RECURRENT RESPIRATORY INFECTIONS
description	Abstract. We performed a study of efficiency for various immunocorrective drugs in a group of 548 young schoolchildren with recurrent respiratory infections. Frequency of respiratory infections and complication rates were taken as endpoints in this study. It was revealed, that preventive immunocorrection by bacterial lysates or glucosamine muramildipeptide combined with vitamin-mineral complexes may reduce frequency of respiratory infections and their complications at statistically significant levels, as well as to restore some abnormal parameters of immune profile, i.e., CD3, CD4, CD16, induced NBT test, IFNγ, TNFα and IgG. Preventive use of Echinaceae purpurae herbae succus or interferon alpha-2b in combination with vitaminmineral complexes statistically significantly reduces only the frequency of respiratory infections, and partially restores some deficient parameters of immune status (IgG, TNFα, CD16). Introduction of preventive immunocorrection in childhood institutions, with > 90 % coverage of children with recurrent respiratory diseases is associated with a decrease in frequency of respiratory infections not only in this cohort, like as among general population of the same age group.
format	article
author	R. V. Maiorov M. V. Chereshneva S. D. Verzilin V. A. Chereshnev
author_facet	R. V. Maiorov M. V. Chereshneva S. D. Verzilin V. A. Chereshnev
author_sort	R. V. Maiorov
title	EFFICIENCY OF SOME IMMUNOMODULATORY DRUGS FOR PREVENTION OF RESPIRATORY INFECTIONS AND THEIR COMPLICATIONS IN YOUNG SCHOOLCHILDREN WITH RECURRENT RESPIRATORY INFECTIONS
title_short	EFFICIENCY OF SOME IMMUNOMODULATORY DRUGS FOR PREVENTION OF RESPIRATORY INFECTIONS AND THEIR COMPLICATIONS IN YOUNG SCHOOLCHILDREN WITH RECURRENT RESPIRATORY INFECTIONS
title_full	EFFICIENCY OF SOME IMMUNOMODULATORY DRUGS FOR PREVENTION OF RESPIRATORY INFECTIONS AND THEIR COMPLICATIONS IN YOUNG SCHOOLCHILDREN WITH RECURRENT RESPIRATORY INFECTIONS
title_fullStr	EFFICIENCY OF SOME IMMUNOMODULATORY DRUGS FOR PREVENTION OF RESPIRATORY INFECTIONS AND THEIR COMPLICATIONS IN YOUNG SCHOOLCHILDREN WITH RECURRENT RESPIRATORY INFECTIONS
title_full_unstemmed	EFFICIENCY OF SOME IMMUNOMODULATORY DRUGS FOR PREVENTION OF RESPIRATORY INFECTIONS AND THEIR COMPLICATIONS IN YOUNG SCHOOLCHILDREN WITH RECURRENT RESPIRATORY INFECTIONS
title_sort	efficiency of some immunomodulatory drugs for prevention of respiratory infections and their complications in young schoolchildren with recurrent respiratory infections
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/b17b7434178f456bb9f71807cd1aec17
work_keys_str_mv	AT rvmaiorov efficiencyofsomeimmunomodulatorydrugsforpreventionofrespiratoryinfectionsandtheircomplicationsinyoungschoolchildrenwithrecurrentrespiratoryinfections AT mvchereshneva efficiencyofsomeimmunomodulatorydrugsforpreventionofrespiratoryinfectionsandtheircomplicationsinyoungschoolchildrenwithrecurrentrespiratoryinfections AT sdverzilin efficiencyofsomeimmunomodulatorydrugsforpreventionofrespiratoryinfectionsandtheircomplicationsinyoungschoolchildrenwithrecurrentrespiratoryinfections AT vachereshnev efficiencyofsomeimmunomodulatorydrugsforpreventionofrespiratoryinfectionsandtheircomplicationsinyoungschoolchildrenwithrecurrentrespiratoryinfections
_version_	1718422441453158400

EFFICIENCY OF SOME IMMUNOMODULATORY DRUGS FOR PREVENTION OF RESPIRATORY INFECTIONS AND THEIR COMPLICATIONS IN YOUNG SCHOOLCHILDREN WITH RECURRENT RESPIRATORY INFECTIONS

Ejemplares similares