Disorder predispositions and protections of Labrador Retrievers in the UK

Abstract The Labrador Retriever is one of the most popular dog breeds worldwide, therefore it is important to have reliable evidence on the general health issues of the breed. Using anonymised veterinary clinical data from the VetCompass Programme, this study aimed to explore the relative risk to co...

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Autores principales:	Camilla Pegram, Charlotte Woolley, Dave C. Brodbelt, David B. Church, Dan G. O’Neill
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b17e04585a414d0bb3638cbb6ded5f20
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spelling	oai:doaj.org-article:b17e04585a414d0bb3638cbb6ded5f202021-12-02T16:14:17ZDisorder predispositions and protections of Labrador Retrievers in the UK10.1038/s41598-021-93379-22045-2322https://doaj.org/article/b17e04585a414d0bb3638cbb6ded5f202021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93379-2https://doaj.org/toc/2045-2322Abstract The Labrador Retriever is one of the most popular dog breeds worldwide, therefore it is important to have reliable evidence on the general health issues of the breed. Using anonymised veterinary clinical data from the VetCompass Programme, this study aimed to explore the relative risk to common disorders in the Labrador Retriever. The clinical records of a random sample of dogs were reviewed to extract the most definitive diagnoses for all disorders recorded during 2016. A list of disorders was generated, including the 30 most common disorders in Labrador Retrievers and the 30 most common disorders in non-Labrador Retrievers. Multivariable logistic regression was used to report the odds of each of these disorders in 1462 (6.6%) Labrador Retrievers compared with 20,786 (93.4%) non-Labrador Retrievers. At a specific-level of diagnostic precision, after accounting for confounding, Labrador Retrievers had significantly increased odds of 12/35 (34.3%) disorders compared to non-Labrador Retrievers; osteoarthritis (OR 2.83) had the highest odds. Conversely, Labrador Retrievers had reduced odds of 7/35 (20.0%) disorders; patellar luxation (OR 0.18) had the lowest odds. This study provides useful information about breed-specific disorder predispositions and protections, which future research could evaluate further to produce definitive guidance for Labrador Retriever breeders and owners.Camilla PegramCharlotte WoolleyDave C. BrodbeltDavid B. ChurchDan G. O’NeillNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Camilla Pegram Charlotte Woolley Dave C. Brodbelt David B. Church Dan G. O’Neill Disorder predispositions and protections of Labrador Retrievers in the UK
description	Abstract The Labrador Retriever is one of the most popular dog breeds worldwide, therefore it is important to have reliable evidence on the general health issues of the breed. Using anonymised veterinary clinical data from the VetCompass Programme, this study aimed to explore the relative risk to common disorders in the Labrador Retriever. The clinical records of a random sample of dogs were reviewed to extract the most definitive diagnoses for all disorders recorded during 2016. A list of disorders was generated, including the 30 most common disorders in Labrador Retrievers and the 30 most common disorders in non-Labrador Retrievers. Multivariable logistic regression was used to report the odds of each of these disorders in 1462 (6.6%) Labrador Retrievers compared with 20,786 (93.4%) non-Labrador Retrievers. At a specific-level of diagnostic precision, after accounting for confounding, Labrador Retrievers had significantly increased odds of 12/35 (34.3%) disorders compared to non-Labrador Retrievers; osteoarthritis (OR 2.83) had the highest odds. Conversely, Labrador Retrievers had reduced odds of 7/35 (20.0%) disorders; patellar luxation (OR 0.18) had the lowest odds. This study provides useful information about breed-specific disorder predispositions and protections, which future research could evaluate further to produce definitive guidance for Labrador Retriever breeders and owners.
format	article
author	Camilla Pegram Charlotte Woolley Dave C. Brodbelt David B. Church Dan G. O’Neill
author_facet	Camilla Pegram Charlotte Woolley Dave C. Brodbelt David B. Church Dan G. O’Neill
author_sort	Camilla Pegram
title	Disorder predispositions and protections of Labrador Retrievers in the UK
title_short	Disorder predispositions and protections of Labrador Retrievers in the UK
title_full	Disorder predispositions and protections of Labrador Retrievers in the UK
title_fullStr	Disorder predispositions and protections of Labrador Retrievers in the UK
title_full_unstemmed	Disorder predispositions and protections of Labrador Retrievers in the UK
title_sort	disorder predispositions and protections of labrador retrievers in the uk
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b17e04585a414d0bb3638cbb6ded5f20
work_keys_str_mv	AT camillapegram disorderpredispositionsandprotectionsoflabradorretrieversintheuk AT charlottewoolley disorderpredispositionsandprotectionsoflabradorretrieversintheuk AT davecbrodbelt disorderpredispositionsandprotectionsoflabradorretrieversintheuk AT davidbchurch disorderpredispositionsandprotectionsoflabradorretrieversintheuk AT dangoneill disorderpredispositionsandprotectionsoflabradorretrieversintheuk
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Disorder predispositions and protections of Labrador Retrievers in the UK

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