Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk

QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique recombinant C. elegans individuals.

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Autores principales: Alejandro Burga, Eyal Ben-David, Tzitziki Lemus Vergara, James Boocock, Leonid Kruglyak
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/b17ed630d0ca4c1388dd18e8c45b47a7
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spelling oai:doaj.org-article:b17ed630d0ca4c1388dd18e8c45b47a72021-12-02T15:35:15ZFast genetic mapping of complex traits in C. elegans using millions of individuals in bulk10.1038/s41467-019-10636-92041-1723https://doaj.org/article/b17ed630d0ca4c1388dd18e8c45b47a72019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10636-9https://doaj.org/toc/2041-1723QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique recombinant C. elegans individuals.Alejandro BurgaEyal Ben-DavidTzitziki Lemus VergaraJames BoocockLeonid KruglyakNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alejandro Burga
Eyal Ben-David
Tzitziki Lemus Vergara
James Boocock
Leonid Kruglyak
Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
description QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique recombinant C. elegans individuals.
format article
author Alejandro Burga
Eyal Ben-David
Tzitziki Lemus Vergara
James Boocock
Leonid Kruglyak
author_facet Alejandro Burga
Eyal Ben-David
Tzitziki Lemus Vergara
James Boocock
Leonid Kruglyak
author_sort Alejandro Burga
title Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
title_short Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
title_full Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
title_fullStr Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
title_full_unstemmed Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
title_sort fast genetic mapping of complex traits in c. elegans using millions of individuals in bulk
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/b17ed630d0ca4c1388dd18e8c45b47a7
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