Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk

QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique recombinant C. elegans individuals.

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Autores principales:	Alejandro Burga, Eyal Ben-David, Tzitziki Lemus Vergara, James Boocock, Leonid Kruglyak
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b17ed630d0ca4c1388dd18e8c45b47a7
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spelling	oai:doaj.org-article:b17ed630d0ca4c1388dd18e8c45b47a72021-12-02T15:35:15ZFast genetic mapping of complex traits in C. elegans using millions of individuals in bulk10.1038/s41467-019-10636-92041-1723https://doaj.org/article/b17ed630d0ca4c1388dd18e8c45b47a72019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10636-9https://doaj.org/toc/2041-1723QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique recombinant C. elegans individuals.Alejandro BurgaEyal Ben-DavidTzitziki Lemus VergaraJames BoocockLeonid KruglyakNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alejandro Burga Eyal Ben-David Tzitziki Lemus Vergara James Boocock Leonid Kruglyak Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
description	QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique recombinant C. elegans individuals.
format	article
author	Alejandro Burga Eyal Ben-David Tzitziki Lemus Vergara James Boocock Leonid Kruglyak
author_facet	Alejandro Burga Eyal Ben-David Tzitziki Lemus Vergara James Boocock Leonid Kruglyak
author_sort	Alejandro Burga
title	Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
title_short	Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
title_full	Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
title_fullStr	Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
title_full_unstemmed	Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
title_sort	fast genetic mapping of complex traits in c. elegans using millions of individuals in bulk
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b17ed630d0ca4c1388dd18e8c45b47a7
work_keys_str_mv	AT alejandroburga fastgeneticmappingofcomplextraitsincelegansusingmillionsofindividualsinbulk AT eyalbendavid fastgeneticmappingofcomplextraitsincelegansusingmillionsofindividualsinbulk AT tzitzikilemusvergara fastgeneticmappingofcomplextraitsincelegansusingmillionsofindividualsinbulk AT jamesboocock fastgeneticmappingofcomplextraitsincelegansusingmillionsofindividualsinbulk AT leonidkruglyak fastgeneticmappingofcomplextraitsincelegansusingmillionsofindividualsinbulk
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Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk

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