Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique recombinant C. elegans individuals.
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Nature Portfolio
2019
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oai:doaj.org-article:b17ed630d0ca4c1388dd18e8c45b47a72021-12-02T15:35:15ZFast genetic mapping of complex traits in C. elegans using millions of individuals in bulk10.1038/s41467-019-10636-92041-1723https://doaj.org/article/b17ed630d0ca4c1388dd18e8c45b47a72019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10636-9https://doaj.org/toc/2041-1723QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique recombinant C. elegans individuals.Alejandro BurgaEyal Ben-DavidTzitziki Lemus VergaraJames BoocockLeonid KruglyakNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Alejandro Burga Eyal Ben-David Tzitziki Lemus Vergara James Boocock Leonid Kruglyak Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk |
description |
QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique recombinant C. elegans individuals. |
format |
article |
author |
Alejandro Burga Eyal Ben-David Tzitziki Lemus Vergara James Boocock Leonid Kruglyak |
author_facet |
Alejandro Burga Eyal Ben-David Tzitziki Lemus Vergara James Boocock Leonid Kruglyak |
author_sort |
Alejandro Burga |
title |
Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk |
title_short |
Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk |
title_full |
Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk |
title_fullStr |
Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk |
title_full_unstemmed |
Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk |
title_sort |
fast genetic mapping of complex traits in c. elegans using millions of individuals in bulk |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/b17ed630d0ca4c1388dd18e8c45b47a7 |
work_keys_str_mv |
AT alejandroburga fastgeneticmappingofcomplextraitsincelegansusingmillionsofindividualsinbulk AT eyalbendavid fastgeneticmappingofcomplextraitsincelegansusingmillionsofindividualsinbulk AT tzitzikilemusvergara fastgeneticmappingofcomplextraitsincelegansusingmillionsofindividualsinbulk AT jamesboocock fastgeneticmappingofcomplextraitsincelegansusingmillionsofindividualsinbulk AT leonidkruglyak fastgeneticmappingofcomplextraitsincelegansusingmillionsofindividualsinbulk |
_version_ |
1718386619177762816 |